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妊娠期甲状腺癌:诊断、管理与治疗。

Thyroid cancer in pregnancy: diagnosis, management, and treatment.

机构信息

Department of Radiology and Biomedical Imaging, Yale School of Medicine, New Haven, CT, USA.

Department of Radiology and Imaging Science, University of Rochester, Rochester, NY, USA.

出版信息

Abdom Radiol (NY). 2023 May;48(5):1724-1739. doi: 10.1007/s00261-023-03808-1. Epub 2023 Jan 31.

Abstract

The evaluation and management of cancer during pregnancy requires special care to assure the health and safety of both the mother and fetus. The diagnosis and treatment of thyroid cancer in the non-pregnant patient often involves radioactive iodine exposure. However, radioactive iodine is contraindicated in pregnancy and surgical interventions pose risks to both the mother and fetus. Thus, the management of thyroid cancer during pregnancy is a unique clinical challenge. In this review, we discuss the imaging of thyroid nodules during pregnancy, including the role of CT, MRI, and nuclear Imaging, as well as that of Ultrasound and FNA. The staging and prognosis are discussed along with the management, treatment, and surveillance of thyroid cancer in pregnancy. Finally, the risks to the fetus through treatment are examined. Case examples are provided with an emphasis on the appropriate direction of care from a radiologist's perspective.

摘要

怀孕期间癌症的评估和管理需要特别注意,以确保母亲和胎儿的健康和安全。非孕妇甲状腺癌的诊断和治疗通常涉及放射性碘暴露。然而,放射性碘在怀孕期间是禁忌的,手术干预对母亲和胎儿都有风险。因此,怀孕期间甲状腺癌的管理是一个独特的临床挑战。在这篇综述中,我们讨论了怀孕期间甲状腺结节的影像学检查,包括 CT、MRI 和核成像的作用,以及超声和细针抽吸活检的作用。我们还讨论了分期和预后,以及怀孕期间甲状腺癌的管理、治疗和监测。最后,我们研究了治疗对胎儿的风险。提供了病例示例,并强调了从放射科医生的角度来看,适当的护理方向。

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