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儿童2型糖尿病的临床表现与治疗

Clinical presentation and treatment of type 2 diabetes in children.

作者信息

Pinhas-Hamiel Orit, Zeitler Phil

机构信息

Pediatric Endocrinology and Diabetes Unit, Safra Children's Hospital, Sheba Medical Center, Tel Hashomer, Ramat Gan, Israel.

出版信息

Pediatr Diabetes. 2007 Dec;8 Suppl 9:16-27. doi: 10.1111/j.1399-5448.2007.00330.x.

Abstract

Type 2 diabetes mellitus (T2DM) has dramatically increased throughout the world in many ethnic groups and among people with diverse social and economic backgrounds. This increase has also affected the young such that over the past decade, the increase in the number of children and youth with T2DM has been labeled an 'epidemic'. Before the 1990s, it was rare for most pediatric centers to have significant numbers of patients with T2DM. However, by 1994, T2DM patients represented up to 16% of new cases of diabetes in children in urban areas and by 1999, depending on geographic location, the range of percentage of new cases because of T2DM was 8-45% and disproportionately represented among minority populations. Although the diagnosis was initially regarded with skepticism, T2DM is now a serious diagnostic consideration in all young people who present with signs and symptoms of diabetes in the USA.

摘要

2型糖尿病(T2DM)在世界各地许多种族群体以及社会经济背景各异的人群中急剧增加。这种增加也影响到了年轻人,以至于在过去十年里,患有T2DM的儿童和青少年人数的增加被称为“流行病”。在20世纪90年代之前,大多数儿科中心很少有大量的T2DM患者。然而,到1994年,T2DM患者在城市儿童糖尿病新病例中所占比例高达16%,到1999年,根据地理位置不同,因T2DM导致的新病例所占百分比范围为8%-45%,且在少数族裔人群中占比过高。尽管最初对该诊断存在怀疑,但如今在美国,对于所有出现糖尿病体征和症状的年轻人而言,T2DM都是一个需要认真考虑的诊断。

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