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WormBase 2007(线虫数据库2007版) (备注:WormBase是一个在线的生物信息学数据库,主要提供线虫相关的数据,这里根据常见理解补充了括号内容,若严格按要求可不加)

WormBase 2007.

作者信息

Rogers Anthony, Antoshechkin Igor, Bieri Tamberlyn, Blasiar Darin, Bastiani Carol, Canaran Payan, Chan Juancarlos, Chen Wen J, Davis Paul, Fernandes Jolene, Fiedler Tristan J, Han Michael, Harris Todd W, Kishore Ranjana, Lee Raymond, McKay Sheldon, Müller Hans-Michael, Nakamura Cecilia, Ozersky Philip, Petcherski Andrei, Schindelman Gary, Schwarz Erich M, Spooner Will, Tuli Mary Ann, Van Auken Kimberly, Wang Daniel, Wang Xiaodong, Williams Gary, Yook Karen, Durbin Richard, Stein Lincoln D, Spieth John, Sternberg Paul W

机构信息

Sanger Institute, Wellcome Trust Genome Campus Hinxton, Cambridgeshire CB10 1SA, UK.

出版信息

Nucleic Acids Res. 2008 Jan;36(Database issue):D612-7. doi: 10.1093/nar/gkm975. Epub 2007 Nov 8.

DOI:10.1093/nar/gkm975
PMID:17991679
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2238927/
Abstract

WormBase (www.wormbase.org) is the major publicly available database of information about Caenorhabditis elegans, an important system for basic biological and biomedical research. Derived from the initial ACeDB database of C. elegans genetic and sequence information, WormBase now includes the genomic, anatomical and functional information about C. elegans, other Caenorhabditis species and other nematodes. As such, it is a crucial resource not only for C. elegans biologists but the larger biomedical and bioinformatics communities. Coverage of core areas of C. elegans biology will allow the biomedical community to make full use of the results of intensive molecular genetic analysis and functional genomic studies of this organism. Improved search and display tools, wider cross-species comparisons and extended ontologies are some of the features that will help scientists extend their research and take advantage of other nematode species genome sequences.

摘要

WormBase(www.wormbase.org)是关于秀丽隐杆线虫信息的主要公开数据库,秀丽隐杆线虫是基础生物学和生物医学研究的重要系统。WormBase源自最初的秀丽隐杆线虫遗传和序列信息数据库ACeDB,现在包含了秀丽隐杆线虫、其他秀丽隐杆线虫物种以及其他线虫的基因组、解剖学和功能信息。因此,它不仅是秀丽隐杆线虫生物学家的重要资源,也是更广泛的生物医学和生物信息学领域的重要资源。秀丽隐杆线虫生物学核心领域的覆盖范围将使生物医学领域能够充分利用对该生物体进行的深入分子遗传学分析和功能基因组学研究的结果。改进的搜索和显示工具、更广泛的跨物种比较以及扩展的本体论是一些有助于科学家扩展其研究并利用其他线虫物种基因组序列的功能。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cb07/2238927/b0b4282fddd0/gkm975f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cb07/2238927/fa514f0c9c05/gkm975f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cb07/2238927/e0fd83c124a2/gkm975f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cb07/2238927/b0b4282fddd0/gkm975f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cb07/2238927/fa514f0c9c05/gkm975f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cb07/2238927/e0fd83c124a2/gkm975f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cb07/2238927/b0b4282fddd0/gkm975f3.jpg

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Comparison of C. elegans and C. briggsae genome sequences reveals extensive conservation of chromosome organization and synteny.秀丽隐杆线虫与briggsae线虫基因组序列的比较揭示了染色体组织和同线性的广泛保守性。
PLoS Biol. 2007 Jul;5(7):e167. doi: 10.1371/journal.pbio.0050167. Epub 2007 Jul 3.
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Impaired processing of FLP and NLP peptides in carboxypeptidase E (EGL-21)-deficient Caenorhabditis elegans as analyzed by mass spectrometry.通过质谱分析羧肽酶E(EGL-21)缺陷型秀丽隐杆线虫中FLP和NLP肽的加工受损情况。
J Neurochem. 2007 Jul;102(1):246-60. doi: 10.1111/j.1471-4159.2007.04474.x.
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Genes misregulated in C. elegans deficient in Dicer, RDE-4, or RDE-1 are enriched for innate immunity genes.
Genetics. 2024 May 7;227(1). doi: 10.1093/genetics/iyae050.
4
Evaluate the Work-Related Exposure of Vanadium on Scalp Hair Samples of Outdoor and Administrative Workers of Oil Drilling Field: Related Health Risks.评估油井作业场户外和行政工作人员的头皮发样中钒的职业暴露:相关健康风险。
Biol Trace Elem Res. 2024 Dec;202(12):5366-5372. doi: 10.1007/s12011-024-04101-y. Epub 2024 Feb 20.
5
Evolution of parasitism genes in the plant parasitic nematodes.寄生性线虫中寄生基因的进化。
Sci Rep. 2024 Feb 14;14(1):3733. doi: 10.1038/s41598-024-54330-3.
6
Stage-specific transcriptome of Bursaphelenchus xylophilus reveals temporal regulation of effector genes and roles of the dauer-like stages in the lifecycle.松材线虫转录组的阶段特异性研究揭示了效应基因的时间调控以及 dauer-like 阶段在生命周期中的作用。
Sci Rep. 2019 Apr 15;9(1):6080. doi: 10.1038/s41598-019-42570-7.
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Sci Rep. 2019 Jan 23;9(1):387. doi: 10.1038/s41598-018-36607-6.
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