Rogers Anthony, Antoshechkin Igor, Bieri Tamberlyn, Blasiar Darin, Bastiani Carol, Canaran Payan, Chan Juancarlos, Chen Wen J, Davis Paul, Fernandes Jolene, Fiedler Tristan J, Han Michael, Harris Todd W, Kishore Ranjana, Lee Raymond, McKay Sheldon, Müller Hans-Michael, Nakamura Cecilia, Ozersky Philip, Petcherski Andrei, Schindelman Gary, Schwarz Erich M, Spooner Will, Tuli Mary Ann, Van Auken Kimberly, Wang Daniel, Wang Xiaodong, Williams Gary, Yook Karen, Durbin Richard, Stein Lincoln D, Spieth John, Sternberg Paul W
Sanger Institute, Wellcome Trust Genome Campus Hinxton, Cambridgeshire CB10 1SA, UK.
Nucleic Acids Res. 2008 Jan;36(Database issue):D612-7. doi: 10.1093/nar/gkm975. Epub 2007 Nov 8.
WormBase (www.wormbase.org) is the major publicly available database of information about Caenorhabditis elegans, an important system for basic biological and biomedical research. Derived from the initial ACeDB database of C. elegans genetic and sequence information, WormBase now includes the genomic, anatomical and functional information about C. elegans, other Caenorhabditis species and other nematodes. As such, it is a crucial resource not only for C. elegans biologists but the larger biomedical and bioinformatics communities. Coverage of core areas of C. elegans biology will allow the biomedical community to make full use of the results of intensive molecular genetic analysis and functional genomic studies of this organism. Improved search and display tools, wider cross-species comparisons and extended ontologies are some of the features that will help scientists extend their research and take advantage of other nematode species genome sequences.