Gründel M, Kopka B, Schulz R
Isotope Laboratory, Institute of Physical Chemistry, Georg-August-University, Tammannstrasse 6, Göttingen, Germany.
Radiat Prot Dosimetry. 2008;129(4):435-8. doi: 10.1093/rpd/ncm459. Epub 2007 Nov 10.
In the departments of nuclear medicine, patients are treated with relatively large activities of (131)I for therapeutic purposes. The applied activities are in the range of 200-10 000 MBq. Consequently, individuals situated in the dwellings of the patients dismissed from the hospital are subjected to an external as well as an internal radioiodine exposition. Internal exposition is due to the inhalation of (131)I exhaled by the patients. In this article, the measurements of radioactivity exhaled by patients with various thyroid diseases, treated with (131)I in the department of Nuclear Medicine of the Radiological Centre in Goettingen and in the Hospital of Nuclear Medicine in Wuerzburg are presented. The measurements of activities exhaled by patients were repeated daily, up to 25 d after the treatment. In addition, the residual activities were monitored by measuring the external dose rates, and by measuring the (131)I activity in the urine of these patients. In some cases, the exhaled radioiodine was separated into three fractions: the elemental, the organically bound and the aerosol-bound iodine fraction. On the basis of the proposed measurements, the doses received by the family members of a discharged patient treated with (131)I were estimated by a model calculation.
在核医学科,为了治疗目的,患者会接受相对大活度的(131)I治疗。所施用的活度范围为200 - 10000 MBq。因此,住在从医院出院的患者家中的人员会受到外部和内部放射性碘照射。内部照射是由于吸入患者呼出的(131)I所致。本文介绍了在哥廷根放射中心核医学科和维尔茨堡核医学医院接受(131)I治疗的各种甲状腺疾病患者呼出放射性的测量情况。对患者呼出活度的测量每天重复进行,直至治疗后25天。此外,通过测量外部剂量率以及测量这些患者尿液中的(131)I活度来监测残留活度。在某些情况下,呼出的放射性碘被分为三个部分:元素碘、有机结合碘和气溶胶结合碘部分。基于所提议的测量,通过模型计算估算了接受(131)I治疗的出院患者家庭成员所接受的剂量。