Maestre J R, Almagro M, Martínez P, de Casas R, Quesada R, Egido J
Servicio de Microbiología Clínica, Hospital Naval de El Ferrol.
Enferm Infecc Microbiol Clin. 1991 Aug-Sep;9(7):394-8.
Two cases of Lyme's disease seen at El Ferrol (Spain) were described. One of them developed a recurrent knee arthritis and the other had a localized sclerodermia (morphea) syndrome. Diagnosis was established by means of clinical picture and serologic tests (enzyme-linked analysis and/or indirect immunofluorescence tests). Joint involvement has often been described in patients diagnosed of having Lyme's disease in Spain, however, the relationship between morphea and borreliosis is still a matter of controversy. We believe that patients with localized sclerodermia and high significant titers of specific antibodies against B. burgdorferi should be treated with antimicrobial agents.
本文描述了在西班牙费罗尔市发现的两例莱姆病病例。其中一例出现复发性膝关节炎，另一例患有局限性硬皮病（硬斑病）综合征。通过临床表现和血清学检测（酶联分析和/或间接免疫荧光检测）确诊。在西班牙，被诊断患有莱姆病的患者中，关节受累情况经常被描述，然而，硬斑病与疏螺旋体病之间的关系仍存在争议。我们认为，患有局限性硬皮病且针对伯氏疏螺旋体的特异性抗体滴度显著升高的患者，应该接受抗菌药物治疗。
