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[Lyme borreliosis: how is it manifested in Spain?].

作者信息

Guerrero A, Quereda C, Martí-Belda P, Escudero R

机构信息

Sección de Enfermedades Infecciosas, Hospital Ramón y Cajal, Universidad de Alcalá de Henares, Madrid.

出版信息

Med Clin (Barc). 1993 May 29;101(1):5-7.

PMID:8315978
Abstract

BACKGROUND

Lyme borreliosis is not usually diagnosed in Spanish patients since before 1987. The aim of this study was to know the clinical spectrum of infection by Borrelia burgdorferi in Spain by a prospective epidemiologic study.

METHODS

The period of collection of cases was from 1987 to 1989 and the follow-up period was of 2 years following diagnosis. Detection of serum antibodies was performed by indirect immunofluorescence and ELISA to patients with clinical suspicion of Lyme borreliosis established in 17 Spanish hospitals. The clinical and serologic data and the possibility of other disease which could justify the symptoms were evaluated with the doctor responsible for the patient.

RESULTS

Fifty-four patients with clinical manifestations and serologic data indicative of the disease and in whom other diagnosis were excluded were detected. Other diseases which could be the cause of the symptomatology were diagnosed in 26 patients with positive serology. Sixty-three percent of the patients had neurologic symptoms, 46% articular symptoms, 44% cutaneous symptoms and 9% cardiac symptoms.

CONCLUSIONS

Lyme borreliosis is not exceptional in Spain. Its clinical spectrum may be situated half way between American and European epidemiologic descriptions. Serology must be interpreted by the clinical manifestations.

摘要

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Appl Environ Microbiol. 2005 Mar;71(3):1336-45. doi: 10.1128/AEM.71.3.1336-1345.2005.
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Molecular and pathogenic characterization of Borrelia burgdorferi sensu lato isolates from Spain.来自西班牙的伯氏疏螺旋体狭义种分离株的分子与致病特征
J Clin Microbiol. 2000 Nov;38(11):4026-33. doi: 10.1128/JCM.38.11.4026-4033.2000.
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Three-year study of antibody to Borrelia burgdorferi in southern Spain.
西班牙南部针对伯氏疏螺旋体抗体的三年研究。
Eur J Clin Microbiol Infect Dis. 1995 Jun;14(6):542-6. doi: 10.1007/BF02113437.