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当今的热疗:电能,癌症治疗的新机遇。

Hyperthermia today: electric energy, a new opportunity in cancer treatment.

作者信息

Fiorentini Giammaria, Szasz Andras

机构信息

Department of Oncology, San Giuseppe General Hospital, Empoli (Florence), Italy.

出版信息

J Cancer Res Ther. 2006 Apr-Jun;2(2):41-6. doi: 10.4103/0973-1482.25848.

Abstract

Hyperthermia is an ancient, but nowadays rapidly developing treatment method in tumor-therapy. Its new paradigm applied in the electro-hyperthermia (oncothermia), which provides energy by means of electric-field and produces non-equilibrium thermal situation in the tissue. The temperature gradients formed in stationary conditions, destroy the membrane of the malignant cells and selectively eliminate the cancer tissue. The characteristic control parameter is the absorbed energy-dose, which is partly used to make the distortions, partly to increase the temperature of the target. This type of technique could be applied for some tumor sites, including brain, soft tissues, liver and abdominal masses, pancreatic cancer, head and neck tumors as well.

摘要

热疗是一种古老但如今在肿瘤治疗中迅速发展的治疗方法。其新范式应用于射频热疗(肿瘤热疗),通过电场提供能量并在组织中产生非平衡热状态。在静态条件下形成的温度梯度会破坏恶性细胞的膜并选择性地消除癌组织。特征控制参数是吸收的能量剂量,其一部分用于产生热畸变,一部分用于提高靶区温度。这种技术可应用于一些肿瘤部位,包括脑、软组织、肝脏和腹部肿块、胰腺癌、头颈部肿瘤等。

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