从自发性血流动力学变异性中识别总外周阻力压力反射冲动反应：通过慢性动脉压力感受器去神经支配进行验证。
Identification of the total peripheral resistance baroreflex impulse response from spontaneous hemodynamic variability: validation by chronic arterial baroreceptor denervation.
作者信息
Chen Xiaoxiao, Kim Jong-Kyung, Sala-Mercado Javier A, Hammond Robert L, Swamy Gokul, Scislo Tadeusz J, O'Leary Donal S, Mukkamala Ramakrishna
机构信息
Department of Electrical and Computer Engineering, Michigan State University, East Lansing, MI 48824, USA.
出版信息
Annu Int Conf IEEE Eng Med Biol Soc. 2007;2007:1051-4. doi: 10.1109/IEMBS.2007.4352475.
We have previously proposed a technique for estimating the static gain values and impulse response of the arterial and cardiopulmonary total peripheral resistance (TPR) baroreflex by mathematical analysis of beat-to-beat fluctuations in arterial blood pressure, cardiac output, and stroke volume. In this study, we evaluated the technique with respect to spontaneous hemodynamic variability measured from seven conscious dogs before and after chronic arterial baroreceptor denervation. Our results show that the technique correctly predicted the alterations in TPR baroreflex functioning that are known to occur following the baroreceptor denervation.
我们之前提出了一种技术，通过对动脉血压、心输出量和每搏输出量逐搏波动进行数学分析，来估计动脉和心肺总外周阻力（TPR）压力反射的静态增益值和脉冲响应。在本研究中，我们针对七只清醒犬在慢性动脉压力感受器去神经支配前后测量的自发性血流动力学变异性，对该技术进行了评估。我们的结果表明，该技术正确地预测了已知在压力感受器去神经支配后发生的TPR压力反射功能的改变。
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