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腰椎间盘退变的改良 Pfirrmann 分级系统

Modified Pfirrmann grading system for lumbar intervertebral disc degeneration.

作者信息

Griffith James F, Wang Yi-Xiang J, Antonio Gregory E, Choi Kai Chow, Yu Alfred, Ahuja Anil T, Leung Ping Chung

机构信息

Department of Diagnostic Radiology and Organ Imaging, Prince of Wales Hospital, Chinese University of Hong Kong, Shatin, NT, Hong Kong.

出版信息

Spine (Phila Pa 1976). 2007 Nov 15;32(24):E708-12. doi: 10.1097/BRS.0b013e31815a59a0.

Abstract

STUDY DESIGN

A reliability study was conducted. OBJECTIVE.: To modify a grading system for lumbar disc degeneration and to test the reliability of this modified grading system.

SUMMARY OF BACKGROUND DATA

The 5-level Pfirrmann grading system for disc degeneration did not prove discriminatory when used to assess disc degeneration in the elderly spine. Such discriminatory power is necessary to test the association between other variables and severity of disc degeneration.

METHODS

An 8-level modified grading system for lumbar disc degeneration was developed including a description of the changes expected for each grade and a 24-image reference panel. The reliability of the modified grading system was tested on 260 lumbar intervertebral discs in 52 subjects (26 men, 26 female) with a mean age of 73 years (range, 67-83 years). All examinations were analyzed independently by 3 readers. Intraobserver and interobserver reliabilities were assessed by calculating weighted kappa statistics.

RESULTS

On average, for all 3 readers, 0.39% of the 260 discs were classified as Grade 2, 22% were classified as Grade 3, 21.5% were classified as Grade 4, 25.3% were classified as Grade 5, 19.1% were classified as Grade 6, 7.1% were classified as Grade 7, and 4.8% were classified as Grade 8. Intraobserver agreement was excellent (weighted kappa range, 0.79-0.91) with substantial interobserver agreement (weighted kappa range, 0.65-0.67). Complete intraobserver agreement was obtained, on average, in 85% of all discs with 84% of disagreement being as a result of a 1 grade difference. Complete interobserver agreement was obtained, on average, in 66% of all discs with 91% of disagreement being as a result of a 1 grade difference.

CONCLUSION

The modified Pfirrmann grading system is useful at discriminating severity of disc degeneration in elderly subjects. The system can be applied with good intra- and interobserver agreement.

摘要

研究设计

进行了一项可靠性研究。

目的

修改腰椎间盘退变的分级系统并测试此修改后分级系统的可靠性。

背景数据总结

用于评估椎间盘退变的5级Pfirrmann分级系统在用于评估老年脊柱的椎间盘退变时未显示出区分能力。这种区分能力对于测试其他变量与椎间盘退变严重程度之间的关联是必要的。

方法

开发了一种用于腰椎间盘退变的8级修改分级系统,包括对每个等级预期变化的描述和一个24幅图像的参考面板。在52名受试者(26名男性,26名女性)的260个腰椎椎间盘中测试了修改后分级系统的可靠性,受试者平均年龄为73岁(范围67 - 83岁)。所有检查均由3名阅片者独立分析。通过计算加权kappa统计量评估观察者内和观察者间的可靠性。

结果

平均而言,对于所有3名阅片者,260个椎间盘中0.39%被分类为2级,22%被分类为3级,21.5%被分类为4级,25.3%被分类为5级,19.1%被分类为6级,7.1%被分类为7级,4.8%被分类为8级。观察者内一致性良好(加权kappa范围为0.79 - 0.91),观察者间一致性较高(加权kappa范围为0.65 - 0.67)。平均而言,在所有椎间盘中85%获得了完全观察者内一致性,84%的不一致是由于相差1个等级。平均而言,在所有椎间盘中66%获得了完全观察者间一致性,91%的不一致是由于相差1个等级。

结论

修改后的Pfirrmann分级系统有助于区分老年受试者椎间盘退变的严重程度。该系统在观察者内和观察者间具有良好的一致性,可予以应用。

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