Pan Wenqi, Wang Jian, Liu Jie, Lu Yan, Huang Bo
Department of Orthopaedics, Affiliated Xinqiao Hospital, the Third Military Medical University, Chongqing, 400037, P.R.China.
Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi. 2012 Dec;26(12):1430-4.
To develop a modified short time inversion recovery (STIR) sequence grading system for lumbar intervertebral disc degeneration based on MRI STIR sequences, and to test the validity and reproducibility of this grading system.
A modified 8-level grading system for lumbar intervertebral disc degeneration based on routine sagittal STIR sequences and modified Pfirrmann grading system was developed. Between April 2011 and February 2012, 60 patients with different degrees of lumbar intervertebral disc degeneration were selected as objects of study, including 32 males and 28 females with an average of 50 years (range, 17-85 years). T2 weighted and STIR sequence images were obtained from the lumbar discs of L1, 2-L5, S1 of each object (total, 300 discs). All examinations were analyzed independently by 3 observers and a consensus readout was performed after all data collected. The validity and reproducibility were analyzed by calculating consistent rate and Kappa value.
According to the grading system, there were 0 grade 1, 83 (27.7%) grade 2, 87 (29.0%) grade 3, 66 (22.0%) grade 4, 31 (10.3%) grade 5, 15 (5.0%) grade 6, 12 (4.0%) grade 7, and 6 (2.0%) grade 8. Intra-observer consistency was strong (Kappa value range, 0.822-0.952), and inter-observer consistency was high to strong (Kappa value range, 0.749-0.843). According to the consensus analysis, the total consistent rate was 82.7%-92.7% (mean, 85.6%). A difference of one grade occurred in 13.9% and a difference of two or more grades in 0.5% of all the cases.
Disc degeneration can be graded by using modified STIR sequence grading system, which can improve the accuracy of grading different degrees of lumbar intervertebral disc degeneration.
基于MRI短时间反转恢复(STIR)序列开发一种改良的腰椎间盘退变STIR序列分级系统,并验证该分级系统的有效性和可重复性。
基于常规矢状位STIR序列和改良的Pfirrmann分级系统,开发一种改良的8级腰椎间盘退变分级系统。2011年4月至2012年2月,选取60例不同程度腰椎间盘退变患者作为研究对象,其中男性32例,女性28例,平均年龄50岁(范围17 - 85岁)。获取每个研究对象L1、2 - L5、S1腰椎间盘的T2加权像和STIR序列图像(共300个椎间盘)。所有检查由3名观察者独立分析,收集所有数据后进行一致性读片。通过计算一致率和Kappa值分析有效性和可重复性。
根据分级系统,1级0例,2级83例(27.7%),3级87例(29.0%),4级66例(22.0%),5级31例(10.3%),6级15例(5.0%),7级12例(4.0%),8级6例(2.0%)。观察者内一致性较强(Kappa值范围0.822 - 0.952),观察者间一致性高到强(Kappa值范围0.749 - 0.843)。根据一致性分析,总一致率为82.7% - 92.7%(平均85.6%)。所有病例中,13.9%出现一级差异,0.5%出现两级或两级以上差异。
改良的STIR序列分级系统可对椎间盘退变进行分级,能提高不同程度腰椎间盘退变分级的准确性。