Schwab Frank, Lafage Virginie, Farcy Jean-Pierre, Bridwell Keith, Glassman Steven, Ondra Stephen, Lowe Tom, Shainline Michael
New York University Hospital for Joint Diseases, New York, NY, USA.
Spine (Phila Pa 1976). 2007 Nov 15;32(24):2723-30. doi: 10.1097/BRS.0b013e31815a58f2.
Multicenter prospective consecutive clinical series.
Investigate the interaction between the Adult Deformity Classification and treatment patterns, surgical strategies, surgery effectiveness, and complication rates.
An Adult Deformity Classification has been established that applies radiographic parameters of disability. Preliminary intraobserver and interobserver analysis reveals excellent reliability of the classification. Outcomes studies have not been reported to date.
A total of 784 adult patients with thoracolumbar or lumbar deformity underwent radiographic evaluation (full-length frontal/sagittal) as well as health assessment: Oswestry Disability Index, Scoliosis Research Society-22, and SF-12. Patients were subdivided by treatment and surgical strategies; 1 year (111 patients) and 2 year (45 patients) follow-up data were analyzed. Interaction between classification, treatment, surgical strategy, health assessment changes, and complications were analyzed.
Classification modifiers (lordosis, subluxation, sagittal balance) were found to have significant variation (higher rates) in surgical care as the grade of the modifier increased. Classification differentiated patients by surgical approach and/or technique. Interaction between classification and baseline health assessment impacts both postoperative health scores and complication rates.
This investigation appears to offer the first comprehensive analysis of classification, treatment, and outcomes in a large adult deformity patient group. Significant treatment patterns and outcomes are coming to light as is the impact of surgical strategy.
多中心前瞻性连续临床系列研究。
研究成人脊柱畸形分类与治疗模式、手术策略、手术效果及并发症发生率之间的相互作用。
已建立一种应用残疾影像学参数的成人脊柱畸形分类方法。初步的观察者内和观察者间分析显示该分类具有极佳的可靠性。目前尚未有关于结局研究的报道。
共784例胸腰段或腰椎畸形成年患者接受了影像学评估(全长正位/侧位)以及健康评估:Oswestry功能障碍指数、脊柱侧弯研究学会-22项问卷和SF-12健康调查简表。患者按治疗和手术策略进行分组;对1年(111例患者)和2年(45例患者)的随访数据进行分析。分析分类、治疗、手术策略、健康评估变化及并发症之间的相互作用。
随着分类修正因素(腰椎前凸、半脱位、矢状面平衡)等级的增加,在手术治疗中发现其有显著差异(发生率更高)。分类可根据手术入路和/或技术区分患者。分类与基线健康评估之间的相互作用对术后健康评分和并发症发生率均有影响。
本研究似乎首次对大量成年脊柱畸形患者群体的分类、治疗及结局进行了全面分析。重要的治疗模式和结局以及手术策略的影响正逐渐显现。