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Adv Exp Med Biol. 2001;492:119-30. doi: 10.1007/978-1-4615-1283-7_10.
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Chemoprevention of colon cancer by organoselenium compounds and impact of high- or low-fat diets.有机硒化合物对结肠癌的化学预防作用以及高脂或低脂饮食的影响。
J Natl Cancer Inst. 1997 Apr 2;89(7):506-12. doi: 10.1093/jnci/89.7.506.
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Inhibition of thymidine kinase in cultured mammary tumor cells by the chemopreventive organoselenium compound, 1,4-phenylenebis(methylene)selenocyanate.
Carcinogenesis. 1994 Apr;15(4):607-10. doi: 10.1093/carcin/15.4.607.
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Evaluation of organoselenium compounds for potential chemopreventive properties in colon carcinogenesis.评估有机硒化合物在结肠癌发生过程中的潜在化学预防特性。
Anticancer Res. 1994 Nov-Dec;14(6B):2509-14.
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Chemoprevention of experimental mammary carcinogenesis by the synthetic organoselenium compound, benzylselenocyanate, in rats.
Carcinogenesis. 1989 Mar;10(3):509-12. doi: 10.1093/carcin/10.3.509.
6
Inhibition of 7,12-dimethylbenz(a)anthracene-induced tumors and DNA adduct formation in the mammary glands of female Sprague-Dawley rats by the synthetic organoselenium compound, 1,4-phenylenebis(methylene)selenocyanate.合成有机硒化合物1,4-亚苯基双（亚甲基）硒氰酸酯对7,12-二甲基苯并（a）蒽诱导的雌性斯普拉格-道利大鼠乳腺肿瘤及DNA加合物形成的抑制作用
Cancer Res. 1992 May 1;52(9):2402-7.

取代苄基硒氰酸酯的简便合成方法。

A facile synthesis of substituted benzyl selenocyanates.

作者信息

Jacob Linda A, Matos Bianca, Mostafa Corey, Rodriguez Joelle, Tillotson Joanne Kivella

机构信息

Division of Natural Sciences, State University of New York at Purchase, Purchase, NY 10577, USA.

出版信息

Molecules. 2004 Jul 31;9(8):622-6. doi: 10.3390/90800622.

DOI:10.3390/90800622
PMID:18007463
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6147281/
Abstract

Benzyl selenocyanates can be made from the corresponding benzylic bromides or chlorides in 30-60 minutes using acetonitrile as a solvent. The products may be obtained pure in satisfactory yields without recourse to chromatography.

摘要

苄基硒氰酸盐可以在30至60分钟内，以乙腈作为溶剂，由相应的苄基溴化物或氯化物制得。产物无需借助色谱法即可获得纯度令人满意且产率良好的纯品。