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[脂质与动脉血压的季节性变化]

[Seasonal variations of lipids and arterial pressure].

作者信息

Roca-Cusachs A, Gómez-Gerique J A, Bou F, Homs R

机构信息

Servicio de Medicina Interna, Hospital de la Santa Creu i Sant Pau., Barcelona.

出版信息

Med Clin (Barc). 1991 Nov 30;97(19):721-5.

PMID:1800859
Abstract

BACKGROUND

The presence of a seasonal variation in serum lipids and blood pressure is often described in the literature.

METHODS

With the aim of analyzing this seasonal influence blood pressure and lipid (total cholesterol and cholesterol corresponding to different lipoprotein, triglycerides and AI and B apolipoprotein families) values were studied over 12 months in 36 normotense healthy males (mean age 36 +/- 6 years), a third of whom presented diverse base lipid alterations. A variance analysis of the relative intraindividual values (to study monthly differences) was carried out and a Student's t test was performed for the absolute values and grouped into two periods (summer and winter) and according to two categories (normal and hyperlipemic).

RESULTS

No significant modification was observed in any of the parameters studied with the exception of the intrapersonal variation coefficient of the triglycerides which was significantly higher in the hyperlipemic individuals.

CONCLUSIONS

In the population studied no seasonal modification was observed in blood pressure or different lipid concentrations analyzed. The slight variation of temperature observed and the elevated sunstroke in Spain in addition to the youth of the population studied may explain the lack of seasonal variation.

摘要

背景

文献中经常描述血清脂质和血压存在季节性变化。

方法

为分析这种季节性影响,对36名血压正常的健康男性(平均年龄36±6岁)进行了为期12个月的血压和脂质(总胆固醇以及与不同脂蛋白、甘油三酯、AI和B载脂蛋白家族相对应的胆固醇)值研究,其中三分之一的人存在不同的基础脂质改变。对个体内相对值进行方差分析(以研究月度差异),并对绝对值进行学生t检验,按两个时期(夏季和冬季)以及两类(正常和高脂血症)进行分组。

结果

除甘油三酯的个体内变异系数在高脂血症个体中显著更高外,在所研究的任何参数中均未观察到显著变化。

结论

在所研究的人群中,未观察到血压或所分析的不同脂质浓度的季节性变化。观察到的温度轻微变化以及西班牙中暑发生率较高,再加上所研究人群较为年轻,可能解释了缺乏季节性变化的原因。

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