[健康新生儿的血脂谱及其与母体血脂水平的相关性]
[Lipid profile in healthy newborn infants and its correlation with maternal lipid levels].
作者信息
Juárez I E, Rivera-Silva G, Mejía-Arangure J M, Mercado-Arellano J A, Díaz-Bensussen S
机构信息
Departamento Clinico, Pediatría Médica Prescolares, Hospital de Pediatría, Centro Médico Nacional Siglo XXI, Instituto Mexicano del Seguro Social (IMSS), México.
出版信息
Salud Publica Mex. 1999 Sep-Oct;41(5):405-9.
OBJECTIVE
To determine serum levels of lipid, cholesterol, triglycerides and lipoproteins in newborns and their mothers and to know the association between them.
MATERIAL AND METHODS
Blood samples were taken from 200 newborns and from their mothers, and analyzed for lipid, cholesterol, triglyceride and lipoprotein content in an autoanalyzer. Data were analyzed with the Epi Info 6 program. Central tendency measurements, variance analysis and Pearson correlation coefficient were obtained.
RESULTS
Average lipid levels in newborn blood samples was 625.2 +/- 130, 158.8 +/- 44 mg/dl of cholesterol, 136.9 +/- 97 mg/dl of triglycerides, 70.5 +/- 23.9 mg/dl LDL, 52.7 +/- 14 mg/dl HDL and 26.5 +/- 15.5 mg/dl VLDL.
CONCLUSIONS
Newborn cholesterol levels were similar to values reported by Alpers and higher than levels published by the American Committee of Pediatric Biochemistry in USA. An association between levels in mothers and their children was found.
目的
测定新生儿及其母亲血清中的脂质、胆固醇、甘油三酯和脂蛋白水平，并了解它们之间的关联。
材料与方法
采集200名新生儿及其母亲的血样，在自动分析仪上分析脂质、胆固醇、甘油三酯和脂蛋白含量。数据用Epi Info 6程序进行分析。获得集中趋势测量值、方差分析和皮尔逊相关系数。
结果
新生儿血样中的平均脂质水平为625.2±130，胆固醇为158.8±44mg/dl，甘油三酯为136.9±97mg/dl，低密度脂蛋白为70.5±23.9mg/dl，高密度脂蛋白为52.7±14mg/dl，极低密度脂蛋白为26.5±15.5mg/dl。
结论
新生儿胆固醇水平与阿尔珀斯报道的值相似，高于美国儿科学会生物化学委员会公布的水平。发现母亲和孩子的水平之间存在关联。
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