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Reversal of chloroquine resistance of 'wild' isolates of Plasmodium falciparum by desipramine.

作者信息

Carosi G, Caligaris S, Fadat G, Castelli F, Matteelli A, Kouka-Bemba D, Roscigno G

机构信息

Department of Infectious and Tropical Diseases, University of Brescia, Italy.

出版信息

Trans R Soc Trop Med Hyg. 1991 Nov-Dec;85(6):723-4. doi: 10.1016/0035-9203(91)90427-z.

DOI:10.1016/0035-9203(91)90427-z
PMID:1801334
Abstract
摘要

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Desipramine and cyproheptadine for reversal of chloroquine resistance in Plasmodium falciparum.去甲丙咪嗪和赛庚啶用于逆转恶性疟原虫对氯喹的耐药性。
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The potential of desipramine to reverse chloroquine resistance of Plasmodium falciparum is reduced by its binding to plasma protein.地昔帕明与血浆蛋白结合后,其逆转恶性疟原虫氯喹耐药性的潜力会降低。
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Relationship of global chloroquine transport and reversal of resistance in Plasmodium falciparum.恶性疟原虫中全球氯喹转运与耐药性逆转的关系
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Dihydroethanoanthracene derivatives as in vitro malarial chloroquine resistance reversal agents.二氢乙烷蒽衍生物作为体外疟原虫氯喹抗性逆转剂
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In vitro increase in chloroquine accumulation induced by dihydroethano- and ethenoanthracene derivatives in Plasmodium falciparum-parasitized erythrocytes.
二氢蒽和乙烯蒽衍生物在恶性疟原虫寄生红细胞中诱导氯喹蓄积的体外研究。
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