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The potential of desipramine to reverse chloroquine resistance of Plasmodium falciparum is reduced by its binding to plasma protein.

作者信息

Boulter M K, Bray P G, Howells R E, Ward S A

机构信息

Tropical Pharmacology Unit, Liverpool School of Tropical Medicine, UK.

出版信息

Trans R Soc Trop Med Hyg. 1993 May-Jun;87(3):303. doi: 10.1016/0035-9203(93)90137-f.

DOI:10.1016/0035-9203(93)90137-f
PMID:8236399
Abstract
摘要

相似文献

1
The potential of desipramine to reverse chloroquine resistance of Plasmodium falciparum is reduced by its binding to plasma protein.地昔帕明与血浆蛋白结合后，其逆转恶性疟原虫氯喹耐药性的潜力会降低。
Trans R Soc Trop Med Hyg. 1993 May-Jun;87(3):303. doi: 10.1016/0035-9203(93)90137-f.
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Desipramine reversal of chloroquine resistance in wild isolates of Plasmodium falciparum.去甲丙咪嗪逆转恶性疟原虫野生分离株对氯喹的耐药性。
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Plasmodium falciparum: detection of P-glycoprotein in chloroquine-susceptible and chloroquine-resistant clones and isolates.
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Uptake and efflux of chloroquine by chloroquine-resistant Plasmodium falciparum clones recently isolated in Africa.近期在非洲分离出的氯喹抗性恶性疟原虫克隆对氯喹的摄取与外排
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Efflux of chloroquine from Plasmodium falciparum: mechanism of chloroquine resistance.
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Antimicrob Agents Chemother. 2001 Nov;45(11):3171-4. doi: 10.1128/AAC.45.11.3171-3174.2001.
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