Ortega Orcos R, Salinero Fort M A, Kazemzadeh Khajoui A, Vidal Aparicio S, de Dios del Valle R
Centro de Salud Doctor Cirajas, Madrid.
Rev Clin Esp. 2007 Dec;207(11):559-62. doi: 10.1157/13111585.
Cross-sectional study to validate a Spanish version of the 5 and 15 items Geriatric Depression Scale (GDS 5 and 15) in a non-selected community dwelling older population, compared with the clinical diagnosis of depression (using DSM-IV criteria) as gold standard.
A total of 301 subjects randomly selected from the >64 years old population served by a public Primary Care Center in Madrid were included. Severe cognitive impairment (MMSE < 20/30), severe hearing impairment and denial to participate were exclusion criteria. A descriptive and a screening study were performed.
The prevalence of depression in this population was 14.6%. The 5- item GDS had a sensitivity of 0.864 (0.762-0.965), specificity of 0.856 (0.813-0.899), PPV 0.507 (0.394-0.62), NPV 0.973 (0.952-0.994), and positive likelihood ratio 6 (4.34-8.26). The 15-item GDS had a sensitivity of 0.818 (0.704-0.932), specificity of 0.977 (0.958-0.995), PPV 0.857 (0.751-0.963), NPV 0.969 (0.948-0.99), and positive likelihood ratio 35.03 (28.76-40.77).
GDS-5 may be useful screening test for depression in non selected elderly patients in primary care. It has better sensitivity than GDS-15 and similar area under curve.
进行横断面研究,在未经过挑选的社区老年人群中验证西班牙语版的5项和15项老年抑郁量表(GDS 5和GDS 15),并将抑郁症的临床诊断(采用DSM-IV标准)作为金标准进行比较。
纳入了从马德里一家公立初级保健中心服务的64岁以上人群中随机选取的301名受试者。排除标准包括严重认知障碍(MMSE<20/30)、严重听力障碍以及拒绝参与。进行了描述性研究和筛查研究。
该人群中抑郁症的患病率为14.6%。5项GDS的灵敏度为0.864(0.762 - 0.965),特异度为0.856(0.813 - 0.899),阳性预测值为0.507(0.394 - 0.62),阴性预测值为0.973(0.952 - 0.994),阳性似然比为6(4.34 - 8.26)。15项GDS的灵敏度为0.818(0.704 - 0.932),特异度为0.977(0.958 - 0.995),阳性预测值为0.857(0.751 - 0.963),阴性预测值为0.969(0.948 - 0.99),阳性似然比为35.03(28.76 - 40.77)。
GDS - 5可能是基层医疗中未经过挑选的老年患者抑郁症的有用筛查测试。它比GDS - 15具有更好的灵敏度,且曲线下面积相似。