评估白细胞酯酶和亚硝酸盐试纸检测法在肝硬化患者中检测自发性细菌性腹膜炎的效果。
Evaluation of leukocyte esterase and nitrite strip tests to detect spontaneous bacterial peritonitis in cirrhotic patients.
作者信息
Torun Serkan, Dolar Enver, Yilmaz Yusuf, Keskin Murat, Kiyici Murat, Sinirtas Melda, Sarandol Emre, Gurel Selim, Nak Selim-Giray, Gulten Macit
机构信息
Uludag University Medical School, Department of Internal Medicine, Bursa 16059, Turkey.
出版信息
World J Gastroenterol. 2007 Dec 7;13(45):6027-30. doi: 10.3748/wjg.v13.45.6027.
AIM
To investigate the diagnostic efficacy of leukocyte esterase and nitrite reagent strips for bedside diagnosis of spontaneous bacterial peritonitis (SBP).
METHODS
A total of 63 consecutive patients with cirrhotic ascites (38 male, 25 female) tested between April 2005 and July 2006 were included in the study. Bedside reagent strip testing was performed on ascitic fluid and the results compared to manual cell counting and ascitic fluid culture. SBP was defined as having a polymorphonuclear ascites count of >or= 250/mm(3).
RESULTS
Fifteen samples showed SBP. The sensitivity, specificity, positive and negative predictive values of the leukocyte esterase reagent strips were; 93%, 100%, 100%, and 98%, respectively. The sensitivity, specificity, positive and negative predictive value of the nitrite reagent strips were 13%, 93%, 40%, and 77%, respectively. The combination of leukocyte esterase and nitrite reagents strips did not yield statistically significant effects on diagnostic accuracy.
CONCLUSION
Leukocyte esterase reagent strips may provide a rapid, bedside diagnostic test for SBP.
目的
探讨白细胞酯酶和亚硝酸盐试剂条对自发性细菌性腹膜炎（SBP）床边诊断的效能。
方法
纳入2005年4月至2006年7月间连续检测的63例肝硬化腹水患者（男性38例，女性25例）。对腹水进行床边试剂条检测，并将结果与手工细胞计数和腹水培养结果进行比较。SBP定义为多形核腹水细胞计数≥250/mm³。
结果
15份样本显示为SBP。白细胞酯酶试剂条的敏感性、特异性、阳性预测值和阴性预测值分别为93%、100%、100%和98%。亚硝酸盐试剂条的敏感性、特异性、阳性预测值和阴性预测值分别为13%、93%、40%和77%。白细胞酯酶和亚硝酸盐试剂条联合使用对诊断准确性没有统计学上的显著影响。
结论
白细胞酯酶试剂条可为SBP提供快速的床边诊断检测。
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