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可逆性后部白质脑病综合征

Reversible posterior leukoencephalopathy syndrome.

作者信息

Moon Jeong Mi, Chun Byeong Jo

机构信息

Department of Emergency Medicine, Chonnam National University Medical School, Gwangju, South Korea.

出版信息

J Emerg Med. 2010 Apr;38(3):e1-4. doi: 10.1016/j.jemermed.2007.06.020. Epub 2007 Nov 19.

Abstract

Reversible posterior leukoencephalopathy syndrome (RPLS) is a neurological disorder characterized by signs of posterior cerebral edema upon radiographic examination. RPLS has been strongly associated with abrupt and significant elevations in blood pressure or the administration of immunosuppressive drugs. Here, we report a case of RPLS occurring in a 30-year-old-mother with a presumed amniotic fluid embolism subsequent to delivery by cesarean section. On the fifth day after the initial successful resuscitation from the cardiorespiratory collapse, she manifested generalized seizure activity and abnormal radiological findings, which were found to be consistent with RPLS. Through our experience, we have suggested that RPLS might occur more easily at lower blood pressures than has been previously recognized. It is important to consider the lower limit at which blood pressure is controlled, especially if accompanied with fever.

摘要

可逆性后部白质脑病综合征(RPLS)是一种神经系统疾病,其特征是影像学检查显示大脑后部水肿迹象。RPLS与血压急剧显著升高或免疫抑制药物的使用密切相关。在此,我们报告一例RPLS病例,该病例发生在一名30岁的母亲身上,她在剖宫产术后疑似发生羊水栓塞。在最初成功从心肺骤停中复苏后的第五天,她出现了全身性癫痫发作活动和异常的影像学表现,这些表现被发现与RPLS一致。根据我们的经验,我们认为RPLS可能在比之前认识到的更低血压水平时更容易发生。考虑血压控制的下限很重要,尤其是在伴有发热的情况下。

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