高效抗逆转录病毒治疗（HAART）开始后黏膜念珠菌病发病率增加：一种良性的免疫重建疾病形式？
Increased incidence of mucosal candidiasis after HAART initiation: a benign form of immune reconstitution disease?
作者信息
Nacher Mathieu, Vantilcke Vincent, Huber Florence, Mahamat Aba, El Guedj Myriam, Randrianjohany Andry, Clyti Emmanuel, Aznar Christine, Carme Bernard, Couppié Pierre
机构信息
COREVIH Cayenne General Hospital, Cayenne, French Guiana.
出版信息
AIDS. 2007 Nov 30;21(18):2534-6. doi: 10.1097/QAD.0b013e3282f02a3a.
Immune reconstitution after HAART initiation is often complicated by adverse clinical manifestations caused either by the unmasking of preexisting untreated opportunistic infections or the clinical deterioration of a known and treated opportunistic infection. The present study was conducted to determine whether the initiation of HAART was followed by an increase in the incidence of mucosal candidiases, a possible manifestation of immune reconstitution disease of the unmasking type.
高效抗逆转录病毒治疗（HAART）开始后的免疫重建常常因以下情况而变得复杂：既往未经治疗的机会性感染被暴露，或者已知并已接受治疗的机会性感染出现临床恶化，从而导致不良临床表现。本研究旨在确定HAART开始后黏膜念珠菌病的发病率是否会增加，黏膜念珠菌病是暴露型免疫重建疾病的一种可能表现。
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