Potma Eric O, Jones David J, Cheng J-X, Xie X S, Ye Jun
Opt Lett. 2002 Jul 1;27(13):1168-70. doi: 10.1364/ol.27.001168.
We demonstrate a significant improvement in signal-to-noise ratio in coherent anti-Stokes Raman scattering (CARS) spectroscopy/microscopy, using two highly synchronized picosecond Ti:sapphire lasers. A temporal jitter between the pulse trains from the two independent commercial lasers is reduced from a few picoseconds to ~21 fs , maintained over several hours. The tight synchronization brings the fluctuation of the CARS signal down to the shot-noise limit, leading to enhanced CARS vibrational images of living cells and polymer beads.
我们展示了在相干反斯托克斯拉曼散射（CARS）光谱学/显微镜技术中，使用两台高度同步的皮秒钛宝石激光器实现的信噪比显著提升。来自两台独立商用激光器的脉冲序列之间的时间抖动从几皮秒降低至约21飞秒，并在数小时内保持稳定。紧密的同步将CARS信号的波动降低到散粒噪声极限，从而得到增强的活细胞和聚合物微珠的CARS振动图像。
