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Sequence-specific cleavage of human telomere DNA by G-quadruplex formation.

作者信息

Xu Yan, Hirohata Youhei, Komiyama Makoto

机构信息

Research Center for Advanced Science and Technology, The University of Tokyo, 4-6-1 Komaba, Meguro-ku, Tokyo 153-8904, Japan.

出版信息

Nucleic Acids Symp Ser (Oxf). 2007(51):199-200. doi: 10.1093/nass/nrm100.

Abstract

In the current study, we reported that oligonucleotide with EDTA-Fe at 5' end causes a sequence specific break in human telomeric DNA strand by G-quadruplex formation.

摘要

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