Suppr超能文献

西班牙老年人髋部骨折的流行病学

Epidemiology of hip fracture in the elderly in Spain.

作者信息

Alvarez-Nebreda M Loreto, Jiménez Ana Belén, Rodríguez Paz, Serra Jose Antonio

机构信息

Geriatrics Department, Hospital General Universitario Gregorio Marañón, Madrid, Spain.

出版信息

Bone. 2008 Feb;42(2):278-85. doi: 10.1016/j.bone.2007.10.001. Epub 2007 Oct 10.

Abstract

OBJECTIVE

To describe the incidence and epidemiological characteristics of hip fracture (HF) in patients aged 65 years or over in the various autonomous regions (AR) of Spain from the year 2000 to 2002 and to determine which factors affect in-hospital mortality.

METHODS

Retrospective, observational study including all patients aged >65 years with acute hip fracture in the 19 AR of Spain from 2000 to 2002. Data were obtained from the National Record of the Minimum Basic Data Set of the Ministry of Health. We analyzed the following: incidence rates (crude and age- and gender-adjusted rates) and incidence of hospital admission by season, length of hospital stay and in-hospital mortality. We used regression analysis to identify the factors that influenced in-hospital mortality.

RESULTS

There were 107,718 cases of HF in patients aged >65 years; of these, 74% were women, with a mean age of 79 years (SD 14). The crude incidence rate for HF was 511 cases per 100,000 >65-year-old patients per year (265 cases per 100,000 men and 688 per 100,000 women and year). Incidence adjusted for age and gender was 503 cases per 100,000 inhabitants per year. Catalonia had the highest age-adjusted incidence and Galicia the lowest (623 and 317 cases per 100,000 inhabitants per year, respectively). Incidence rates increased from spring (24.1%) to winter (25.8%). The mean length of hospital stay was 15 days (SD 13). Seasonal influence and length of stay varied greatly between autonomous regions. While the overall in-hospital mortality rate was 5.3%, the rate for males was double that of females (8.9% and 4.8%, respectively), and in-hospital mortality increased with comorbidity (each point on the Charlson index increased mortality by 34.5%) was higher in winter (11% more risk compared to warmer seasons) and in cold climate regions (15% more risk compared to regions with a warm climate, i.e.: Catalonia, Valencia, Murcia, Andalusia, Balearic Islands and Canary Islands).

CONCLUSIONS

Hip fracture mainly affects elderly women and presents great variability in incidence, seasonality, length of hospital stay and mortality between the different autonomous regions in Spain. Elderly male patients with severe comorbid conditions, who are admitted in winter and in cold climate regions are more at risk of in-hospital mortality.

摘要

目的

描述2000年至2002年西班牙各自治区65岁及以上患者髋部骨折(HF)的发病率及流行病学特征,并确定影响住院死亡率的因素。

方法

回顾性观察性研究,纳入2000年至2002年西班牙19个自治区所有年龄>65岁的急性髋部骨折患者。数据来自卫生部的国家最低基本数据集记录。我们分析了以下内容:发病率(粗发病率以及年龄和性别调整后的发病率)、按季节划分的住院率、住院时间和住院死亡率。我们使用回归分析来确定影响住院死亡率的因素。

结果

65岁及以上患者中有107,718例髋部骨折病例;其中,74%为女性,平均年龄79岁(标准差14)。髋部骨折的粗发病率为每年每10万名65岁以上患者511例(每10万名男性265例,每10万名女性每年688例)。经年龄和性别调整后的发病率为每年每10万居民503例。加泰罗尼亚的年龄调整发病率最高,加利西亚最低(分别为每年每10万居民623例和317例)。发病率从春季(24.1%)到冬季(25.8%)有所上升。平均住院时间为15天(标准差13)。各自治区之间的季节影响和住院时间差异很大。虽然总体住院死亡率为5.3%,但男性死亡率是女性的两倍(分别为8.9%和4.8%),住院死亡率随合并症增加(查尔森指数每增加1分,死亡率增加34.5%),冬季更高(与温暖季节相比风险高11%),在寒冷气候地区也更高(与气候温暖地区相比风险高15%,即:加泰罗尼亚、巴伦西亚、穆尔西亚、安达卢西亚、巴利阿里群岛和加那利群岛))。

结论

髋部骨折主要影响老年女性,在西班牙不同自治区之间,其发病率、季节性、住院时间和死亡率存在很大差异。冬季在寒冷气候地区住院的患有严重合并症的老年男性患者住院死亡风险更高。

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验