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[活性氧与真菌抗氧化防御策略:综述]

[Reactive oxygen species and the strategy of the antioxidant defense in fungi: a review].

作者信息

Belozerskaia T A, Gessler N N

出版信息

Prikl Biokhim Mikrobiol. 2007 Sep-Oct;43(5):565-75.

PMID:18038677
Abstract

The level of reactive oxygen species (ROS) in the cell regulates the growth and differentiation of the fungal organism. This review considers the pathways of generation of the primary ROS and the defense methods used by fungi and yeasts against them as well as the involvement of thiol compounds in the antioxidant defense of the fungal cell. It is demonstrated that the adaptation of fungi to oxidative stress is tightly connected with the redox-dependent changes in the activities of antioxidant defense components.

摘要

细胞内活性氧(ROS)的水平调节着真菌生物体的生长和分化。本综述探讨了主要ROS的产生途径、真菌和酵母抵御ROS的防御方法以及硫醇化合物在真菌细胞抗氧化防御中的作用。研究表明,真菌对氧化应激的适应与抗氧化防御成分活性的氧化还原依赖性变化密切相关。

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