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皮肤胶原蛋白羟基化与年龄的关系:对人体皮肤的分析

[Hydroxylation of skin collagen in relation to age: analyses of the human skin].

作者信息

Ali M, Ruiz-Torres A

出版信息

Aktuelle Gerontol. 1977 May;7(5):263-6.

PMID:18040
Abstract

The results of human skin analysis are demonstrated. It has been pointed out, that the content of hydroxyproline and hydroxylysine, in addition to the usual variation as the other aminoacids varies extensively. The extent of hydroxylation was estimated from the relation of OH-aminoacids to (not hydroxylated) each other. The determined variation of the results is most probably due to a different collagen hydroxylation within the biological dispersion. An age-related degree of hydroxylation could not be detected.

摘要

展示了人体皮肤分析的结果。已经指出,除了与其他氨基酸一样存在通常的变化外,羟脯氨酸和羟赖氨酸的含量变化很大。根据羟基氨基酸与(未羟基化的)彼此之间的关系来估计羟基化程度。结果确定的变化很可能是由于生物分散体内不同的胶原蛋白羟基化所致。未检测到与年龄相关的羟基化程度。

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