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一种用于测量通气新生儿吸入气体温度的实验模型。

An experimental model for the measurement of inspired gas temperatures in ventilated neonates.

作者信息

Jardine Luke Anthony, Dunster Kimble Robert, Davies Mark William

机构信息

Grantley Stable Neonatal Unit, Royal Brisbane and Women's Hospital, Brisbane, University of Queensland, Australia.

出版信息

Pediatr Pulmonol. 2008 Jan;43(1):29-33. doi: 10.1002/ppul.20731.

Abstract

OBJECTIVE

To determine the inspired gas temperature at points from the endo-tracheal tube (ETT) circuit manifold to the tip of the ETT in a model neonatal lung.

DESIGN

A model lung attached to standard ventilator circuit, autofeed chamber and humidifier was ventilated using typical pressure-limited, time cycled settings. Temperatures were measured at various distances along the ETT using a K-type thermocouple temperature probe.

RESULTS

The inspired gas temperature dropped from the circuit temperature probe site (40 degrees C) to the proximal end of the ETT (37 degrees C). The temperature dropped further as it passed through the exposed part of the ETT (34 degrees C) but then warmed again on entering the lung model so that the inspired gas at the distal end of the ETT was 37 degrees C. Statistically significant differences were found with a one-way ANOVA P-value of <0.0001. The differences between each pair of mean temperatures were statistically significant (all P<0.001) except when comparing the proximal end of the ETT with midway down the ETT (Bonferroni's Multiple Comparison Test, P>0.05).

CONCLUSIONS

Inspired gas temperature drops as it passes through the circuit temperature probe site, the proximal end of the ETT and the exposed part of the ETT. The inspired gas rewarms on entering the model lung and exits the ETT at the desired temperature. The effect of measuring temperature closer to the patient, setting the circuit temperature higher and/or increasing the ambient temperature through which the circuit passes, need to be evaluated.

摘要

目的

在新生儿肺模型中,确定从气管内导管(ETT)回路歧管到ETT尖端各点处的吸入气体温度。

设计

将一个与标准呼吸机回路、自动给液室和加湿器相连的模型肺,使用典型的压力限制、时间切换设置进行通气。使用K型热电偶温度探头沿着ETT在不同距离处测量温度。

结果

吸入气体温度从回路温度探头部位(40摄氏度)下降到ETT近端(37摄氏度)。当它通过ETT的暴露部分时温度进一步下降(34摄氏度),但在进入肺模型时又再次升温,使得ETT远端的吸入气体温度为37摄氏度。通过单因素方差分析发现具有统计学显著差异,P值<0.0001。除了比较ETT近端与ETT中部时(Bonferroni多重比较检验,P>0.05),每对平均温度之间的差异均具有统计学显著性(所有P<0.001)。

结论

吸入气体在通过回路温度探头部位、ETT近端和ETT暴露部分时温度下降。吸入气体在进入模型肺时重新升温,并在所需温度下离开ETT。需要评估更靠近患者测量温度、将回路温度设置得更高和/或提高回路所经过的环境温度的效果。

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