Schwartz Michael D, Geller Robert J
Georgia Poison Center/Emory University School of Medicine, Atlanta, Georgia, USA.
Ther Drug Monit. 2007 Dec;29(6):843-4. doi: 10.1097/FTD.0b013e31815bf239.
Lamotrigine is a commonly prescribed anticonvulsant medication. It is an infrequently reported agent of intentional acute ingestion to poison centers. The spectra of clinical effects of lamotrigine in acute overdose are not well established. We report a case of acute ingestion of lamotrigine and ethanol that resulted in coma requiring ventilatory support, paradoxic seizure activity, and mild rhabdomyolysis.
拉莫三嗪是一种常用的抗惊厥药物。它是一种向中毒控制中心报告较少的故意急性摄入药物。拉莫三嗪急性过量的临床效应谱尚未完全明确。我们报告一例拉莫三嗪与乙醇急性摄入导致昏迷需要通气支持、反常癫痫活动及轻度横纹肌溶解的病例。
