Yanagisawa T, Kosakai K, Izawa C, Tomiyama T, Yasunami M
Kotobuki Seiyaku Co., Ltd., Nagano, Japan.
Chem Pharm Bull (Tokyo). 1991 Sep;39(9):2429-32. doi: 10.1248/cpb.39.2429.
The metabolites of sodium 3-ethyl-7-isopropyl-1-azulenesulfonate (KT1-32, 1), a candidate as an anti-ulcer drug, and related compounds were synthesized. The effects of the compounds on anti-peptic activity were determined as compared to that of 1.
合成了作为抗溃疡药物候选物的3-乙基-7-异丙基-1-薁磺酸钠(KT1-32,1)及其相关化合物的代谢产物。与化合物1相比,测定了这些化合物的抗消化活性。