Fischer Thomas, Singer Adam J, Lee Christopher, Thode Henry C
Department of Emergency Medicine, Stony Brook University Medical Center, Stony Brook, NY, USA.
Acad Emerg Med. 2007 Dec;14(12):1172-5. doi: 10.1197/j.aem.2007.07.011.
Withholding antibiotics in nontoxic children with acute otitis media (AOM) is now recommended to reduce bacterial resistance rates. Using the National Hospital Ambulatory Medical Care Survey (NHAMCS), the authors describe the national trends for prescribing antibiotics in children with AOM presenting to emergency departments (EDs) in the United States over the past decade. The authors hypothesized that the rates of prescribing antibiotics would decline over time.
This was a retrospective study of NHAMCS databases. A national sampling of ED visits for 1996-2005 was used to identify trends in ED prescription of antibiotics to patients with AOM. The National Drug Code Directory Drug Classes were used to identify type of antibiotic prescribed. Frequency and type of antibiotic prescription patterns over time were evaluated.
There were 2.6 million and 2.1 million ED visits for AOM during the first and last years of the study. Children ages 2-12 years accounted for about 40% of all ED visits for AOM, with another 40% in the younger than 2 years age group and 20% in the older than 12 years of age group. During the first and last year of the study, 79.2% and 91.3% of the patients with AOM were prescribed antibiotics, respectively. There was a slight increasing trend in the proportion prescribed antibiotics over time (p = 0.02). The rates of use of antibiotics for AOM were similar in all three age groups.
There was a slight increase in the percentage of children with AOM who were prescribed antibiotics in the ED between 1996 and 2005. There was also no change in the patterns of prescribing antibiotics.
目前建议对无中毒症状的急性中耳炎(AOM)患儿不使用抗生素,以降低细菌耐药率。作者利用国家医院门诊医疗调查(NHAMCS),描述了过去十年美国急诊科(ED)中AOM患儿抗生素处方的全国趋势。作者假设抗生素处方率会随时间下降。
这是一项对NHAMCS数据库的回顾性研究。采用1996 - 2005年全国急诊科就诊抽样数据来确定急诊科对AOM患者抗生素处方的趋势。使用国家药品代码目录药物类别来确定所开抗生素的类型。评估随时间变化的抗生素处方模式的频率和类型。
在研究的第一年和最后一年,分别有260万和210万例AOM患者到急诊科就诊。2至12岁的儿童约占所有AOM患者急诊科就诊人数的40%,2岁以下年龄组占另外40%,12岁以上年龄组占20%。在研究的第一年和最后一年,分别有79.2%和91.3%的AOM患者被开具了抗生素。随时间推移,开具抗生素的比例有轻微上升趋势(p = 0.02)。AOM抗生素的使用在所有三个年龄组中相似。
1996年至2005年间,在急诊科被开具抗生素的AOM患儿比例略有增加。抗生素处方模式也没有变化。