Barbetakis Nikolaos, Samanidis Georgios, Samanidou Elpida, Kirodimos Efthimios, Kiziridou Anastasia, Bischiniotis Theodoros, Tsilikas Christodoulos
Thoracic Surgery Department, Theagenio Cancer Hospital, Thessaloniki, Greece.
J Med Case Rep. 2007 Nov 30;1:161. doi: 10.1186/1752-1947-1-161.
Liposarcoma is the most commonly diagnosed soft tissue sarcoma in adults and occurs predominantly in the lower limbs and retroperitoneum. Primary mediastinal liposarcomas are rare.They are often asymptomatic and when growing to large size the presenting symptoms are related to direct invasion or compression of other thoracic organs such as the heart, great vessels and lung.
A case of a 68-year-old man with primary mediastinal liposarcoma involving the diaphragm and pericardium and successfully managed by complete surgical excision is presented. The patient's postoperative course was uneventful with no evidence of recurrence 9 months after the operation.
Surgical removal is the optimal treatment for a mediastinal liposarcoma. If the entire tumor can not be resected, surgical debulking often results in symptomatic relief. International literature has demonstrated that recurrent disease occurs and therefore a long-term careful follow up is required.
脂肪肉瘤是成人中最常被诊断出的软组织肉瘤，主要发生在下肢和腹膜后。原发性纵隔脂肪肉瘤罕见。它们通常无症状，当生长到较大尺寸时，出现的症状与直接侵犯或压迫其他胸部器官（如心脏、大血管和肺）有关。
本文介绍了一例68岁男性原发性纵隔脂肪肉瘤累及膈肌和心包，并通过完整手术切除成功治疗的病例。患者术后恢复顺利，术后9个月无复发迹象。
手术切除是纵隔脂肪肉瘤的最佳治疗方法。如果不能切除整个肿瘤，手术减瘤通常可缓解症状。国际文献表明会出现复发病例，因此需要长期密切随访。
