[采用高效液相色谱法和SIEAP质谱法对多烯大环内酯类抗生素标准品成分的研究]
[Study of components of standard samples of polyene macrolide antibiotics by the methods of high performance liquid chromatography and SIEAP mass spectrometry].
作者信息
Mitrofanova V G, Mirgorodskaia O A, Derzhavets A A, Matveeva E R, Shenin Iu D, Morgunova A F
出版信息
Antibiot Khimioter. 1991 Oct;36(10):9-11.
PMID:1805702
Abstract
The component composition of reference samples of polyenic macrolide antibiotics such as nystatin, mycoheptin, amphotericin B and levorin was studied by HPLC and chromatographic mass spectrometry in comparison to the WHO standards. It was shown that the samples were close by their component composition to the analogous samples of the WHO standards.
摘要
通过高效液相色谱法（HPLC）和色谱质谱联用技术，与世界卫生组织（WHO）标准相比，对制霉菌素、抗霉菌素、两性霉素B和左霉素等多烯大环内酯类抗生素参考样品的成分组成进行了研究。结果表明，这些样品的成分组成与WHO标准的类似样品相近。
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