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与二次髋部骨折相关的因素:一项系统综述。

Factors associated with a second hip fracture: a systematic review.

作者信息

Egan Mary, Jaglal Susan, Byrne Kerry, Wells Jennie, Stolee Paul

机构信息

School of Rehabilitation Sciences, University of Ottawa, Ottawa, Ontario, Canada.

出版信息

Clin Rehabil. 2008 Mar;22(3):272-82. doi: 10.1177/0269215507081573. Epub 2007 Dec 5.

Abstract

OBJECTIVE

To provide a systematic review of factors associated with subsequent hip fracture among individuals who have fractured a hip.

DATA SOURCES

We searched Ageline, CINAHL, EMBASE and MEDLINE, from database inceptions to the week of 5 June 2006.

REVIEW METHODS

Studies were selected if they provided information regarding risk of subsequent hip fracture among individuals who had fractured a hip. Study quality was assessed using the Jadad criteria for randomized controlled trials (RCTs) and a simple scale based on the MOOSE criteria for cohort studies.

RESULTS

Four RCTs and seven cohort studies were identified. Older age, cognitive impairment and lower bone mass appear to increase the risk of subsequent fracture, as did impaired depth perception, impaired mobility, previous falls, dizziness and poor or fair self-perceived health. Pharmacologic treatment for osteoporosis decreased the risk of subsequent fracture. Use of hip protectors by community-dwelling seniors did not appear to protect against a second fracture.

CONCLUSION

A number of easily observed risk factors may help identify those individuals at higher risk for subsequent fracture.

摘要

目的

对髋部骨折患者后续发生髋部骨折的相关因素进行系统综述。

数据来源

我们检索了从数据库建立至2006年6月5日当周的Ageline、CINAHL、EMBASE和MEDLINE数据库。

综述方法

如果研究提供了有关髋部骨折患者后续发生髋部骨折风险的信息,则将其纳入。采用Jadad随机对照试验(RCT)标准和基于队列研究MOOSE标准的简易量表评估研究质量。

结果

共纳入4项随机对照试验和7项队列研究。年龄较大、认知障碍和骨量较低似乎会增加后续骨折的风险,深度感知受损、行动能力受损、既往跌倒、头晕以及自我感觉健康状况差或一般也会增加风险。骨质疏松症的药物治疗可降低后续骨折的风险。社区居住老年人使用髋部保护器似乎并不能预防再次骨折。

结论

一些易于观察到的风险因素可能有助于识别那些后续骨折风险较高的个体。

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