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一名接受双膦酸盐治疗骨质疏松症的患者在股骨转子下骨折固定过程中意外发生医源性股骨颈骨折:病例报告。

Unexpected iatrogenic fracture of the femoral neck during subtrochanteric fracture fixation in a patient on bisphosphonate treatment for osteoporosis: Case report.

作者信息

Barimani Bardia, Khan Kashif, Abduljabbar Fahad, Volesky Monica, Antoniou John

机构信息

Department of Orthopedic Surgery, McGill University Health Centre, Montreal, Canada.

Department of Experimental Surgery, McGill University Health Centre, Montreal, Canada.

出版信息

Trauma Case Rep. 2020 Mar 7;26:100290. doi: 10.1016/j.tcr.2020.100290. eCollection 2020 Apr.

DOI:10.1016/j.tcr.2020.100290
PMID:32181318
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7062943/
Abstract

Osteoporotic patients being treated with bisphosphonates present an interesting dilemma when removing hardware such as dynamic hip screws "DHS". In this paper, we describe the case of a 66-year-old osteoporotic patient who was placed on long term bisphosphonate therapy after sustaining an intertrochanteric hip fracture which was stabilized with a DHS. She presented with a subtrochantric fracture on the ipsilateral side. She was planned for DHS removal and intramedullary nailing. Removal of the dynamic hip screw proved to be difficult, likely due to possible cold welding of the DHS to the barrel of the side plate and sclerotic bone formation around the hardware secondary to the extended bisphosphonate use. The patient had an intra-operative femoral neck fracture while attempting the DHS removal. We had to convert to an unanticipated total hip replacement. Careful considerations should be taken when removing hardware from patients on long term bisphosphonate treatment.

摘要

对于正在接受双膦酸盐治疗的骨质疏松患者,在取出诸如动力髋螺钉(DHS)等内固定装置时会面临一个有趣的难题。在本文中,我们描述了一名66岁骨质疏松患者的病例,该患者在转子间髋部骨折后接受了长期双膦酸盐治疗,骨折用DHS固定。她出现了同侧转子下骨折。计划为其取出DHS并进行髓内钉固定。事实证明,取出动力髋螺钉很困难,这可能是由于DHS与侧板的桶形部分可能发生冷焊,以及长期使用双膦酸盐导致内固定装置周围形成硬化骨。患者在尝试取出DHS时发生了术中股骨颈骨折。我们不得不转为进行意外的全髋关节置换。对于长期接受双膦酸盐治疗的患者,在取出内固定装置时应谨慎考虑

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6e6e/7062943/37a8bba8f3ad/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6e6e/7062943/f0a07f9a4b71/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6e6e/7062943/1ac48c061d4c/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6e6e/7062943/c3fb38552694/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6e6e/7062943/37a8bba8f3ad/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6e6e/7062943/f0a07f9a4b71/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6e6e/7062943/1ac48c061d4c/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6e6e/7062943/c3fb38552694/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6e6e/7062943/37a8bba8f3ad/gr4.jpg

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本文引用的文献

1
Atypical femoral fractures and bisphosphonate use: current evidence and clinical implications.非典型股骨骨折与双膦酸盐的使用:当前证据及临床意义
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The proximal femur nail antirotation: an identifiable improvement in the treatment of unstable pertrochanteric fractures?股骨近端抗旋髓内钉:在不稳定型股骨转子间骨折治疗中是一项可识别的进步吗?
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Histological finding of atypical subtrochanteric fracture after long-term alendronate therapy.长期阿仑膦酸盐治疗后非典型转子下骨折的组织学发现。
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Long-term use of bisphosphonates in osteoporosis.骨质疏松症中长期使用双磷酸盐。
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Atypical fractures of the femoral diaphysis in postmenopausal women taking alendronate.服用阿仑膦酸盐的绝经后女性股骨干非典型骨折。
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8
An emerging pattern of subtrochanteric stress fractures: a long-term complication of alendronate therapy?粗隆下应力性骨折的一种新出现模式:阿仑膦酸盐治疗的一种长期并发症?
Injury. 2008 Feb;39(2):224-31. doi: 10.1016/j.injury.2007.08.036. Epub 2008 Jan 28.
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Factors associated with a second hip fracture: a systematic review.与二次髋部骨折相关的因素:一项系统综述。
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