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东亚人群的代谢综合征

The metabolic syndrome in East Asians.

作者信息

Hoang Khiet C, Le Truc Vy, Wong Nathan D

机构信息

Heart Disease Prevention Program, Division of Cardiology, University of California, Irvine, CA 92697, USA.

出版信息

J Cardiometab Syndr. 2007 Fall;2(4):276-82. doi: 10.1111/j.1559-4564.2007.07491.x.

Abstract

The metabolic syndrome is an emerging epidemic in developing nations, including East Asian countries such as China, Japan, and Korea. Studies examining the metabolic syndrome have used different definitions, with prevalence often highly dependent on the cut points for abdominal obesity utilized, which have been recommended by the International Diabetes Federation to be lower than standards used in Caucasians and other ethnic groups. Prevalence rates have generally varied from 8% to 13% in men and 2% to 18% in women, depending on ethnic group and definition used, and are consistently lower than most Western Caucasian populations. While recent dramatic changes in lifestyle from Westernization of dietary habits and reduced physical activity present challenges, an emphasis on healthful lifestyle changes remains the cornerstone for metabolic syndrome management. In addition, clinical management focusing on control of obesity, elevated blood pressure, dyslipidemia, and hyperglycemia, with consideration of pharmacologic therapy issues unique to certain Asian populations, remains important for reducing associated cardiometabolic risks.

摘要

代谢综合征在包括中国、日本和韩国等东亚国家在内的发展中国家正成为一种新出现的流行病。研究代谢综合征时采用了不同的定义,患病率往往高度依赖于所使用的腹部肥胖切点,国际糖尿病联盟建议这些切点低于白种人和其他种族群体所使用的标准。根据种族群体和所使用的定义,男性患病率一般在8%至13%之间,女性患病率在2%至18%之间,并且始终低于大多数西方白种人群体。虽然饮食习惯西化和身体活动减少等近期生活方式的巨大变化带来了挑战,但强调健康的生活方式改变仍然是代谢综合征管理的基石。此外,注重控制肥胖、高血压、血脂异常和高血糖,并考虑某些亚洲人群特有的药物治疗问题的临床管理,对于降低相关的心脑血管代谢风险仍然很重要。

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