Dekker J J M, Koelen J A, Van H L, Schoevers R A, Peen J, Hendriksen M, Kool S, Van Aalst G, De Jonghe F
Clinical Psychology, Vrije Universiteit, Amsterdam, The Netherlands.
J Affect Disord. 2008 Jul;109(1-2):183-8. doi: 10.1016/j.jad.2007.10.015. Epub 2007 Dec 3.
To examine the efficacy and speed of action of short-term psychodynamic supportive psychotherapy (SPSP) in comparison to pharmacotherapy (PhT) in the acute treatment of depression.
This study reported on the first 8 weeks of a treatment algorithm for depression. 70 patients with a depressive episode according to DSM-IV were randomized to PhT, 71 patients were randomized to SPSP. The acceptability of the psychotherapy was greater than pharmacotherapy.
At the end of the first 8 weeks of treatment, attrition rates were similar in both conditions. PhT-patients were better off at 4 weeks according to two of the four measures The superiority of PhT was clearer on the self-report than on the independent measure.
There are signs that the benefits of PhT over SPSP--where detected--are short-lived and cover mostly the first month of treatment. The progression of these patients through the rest of their treatments, and afterwards, will be reported in further contributions.
比较短期心理动力支持性心理治疗（SPSP）与药物治疗（PhT）在抑郁症急性治疗中的疗效和起效速度。
本研究报告了抑郁症治疗方案的前8周情况。70例符合《精神疾病诊断与统计手册》第四版（DSM-IV）中抑郁发作标准的患者被随机分配至药物治疗组，71例患者被随机分配至短期心理动力支持性心理治疗组。心理治疗的可接受性高于药物治疗。
在治疗的前8周结束时，两种治疗条件下的脱落率相似。根据四项测量指标中的两项，药物治疗组患者在4周时情况更好。药物治疗在自我报告方面的优势比在独立测量方面更明显。
有迹象表明，药物治疗相对于短期心理动力支持性心理治疗的益处（若能检测到）是短暂的，且主要涵盖治疗的第一个月。这些患者在后续治疗过程及之后的情况将在进一步的报告中呈现。
