起效速度：在抑郁症治疗方案的前8周中，短期心理动力支持性心理治疗与药物治疗的相对疗效。
Speed of action: the relative efficacy of short psychodynamic supportive psychotherapy and pharmacotherapy in the first 8 weeks of a treatment algorithm for depression.
作者信息
Dekker J J M, Koelen J A, Van H L, Schoevers R A, Peen J, Hendriksen M, Kool S, Van Aalst G, De Jonghe F
机构信息
Clinical Psychology, Vrije Universiteit, Amsterdam, The Netherlands.
出版信息
J Affect Disord. 2008 Jul;109(1-2):183-8. doi: 10.1016/j.jad.2007.10.015. Epub 2007 Dec 3.
OBJECTIVE
To examine the efficacy and speed of action of short-term psychodynamic supportive psychotherapy (SPSP) in comparison to pharmacotherapy (PhT) in the acute treatment of depression.
METHOD
This study reported on the first 8 weeks of a treatment algorithm for depression. 70 patients with a depressive episode according to DSM-IV were randomized to PhT, 71 patients were randomized to SPSP. The acceptability of the psychotherapy was greater than pharmacotherapy.
RESULTS
At the end of the first 8 weeks of treatment, attrition rates were similar in both conditions. PhT-patients were better off at 4 weeks according to two of the four measures The superiority of PhT was clearer on the self-report than on the independent measure.
CONCLUSIONS
There are signs that the benefits of PhT over SPSP--where detected--are short-lived and cover mostly the first month of treatment. The progression of these patients through the rest of their treatments, and afterwards, will be reported in further contributions.
目的
比较短期心理动力支持性心理治疗（SPSP）与药物治疗（PhT）在抑郁症急性治疗中的疗效和起效速度。
方法
本研究报告了抑郁症治疗方案的前8周情况。70例符合《精神疾病诊断与统计手册》第四版（DSM-IV）中抑郁发作标准的患者被随机分配至药物治疗组，71例患者被随机分配至短期心理动力支持性心理治疗组。心理治疗的可接受性高于药物治疗。
结果
在治疗的前8周结束时，两种治疗条件下的脱落率相似。根据四项测量指标中的两项，药物治疗组患者在4周时情况更好。药物治疗在自我报告方面的优势比在独立测量方面更明显。
结论
有迹象表明，药物治疗相对于短期心理动力支持性心理治疗的益处（若能检测到）是短暂的，且主要涵盖治疗的第一个月。这些患者在后续治疗过程及之后的情况将在进一步的报告中呈现。
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