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维也纳艾滋病毒感染者中非法药物和多药物使用的流行情况及关联。

Prevalence and Associations of Illicit Drug and Polydrug Use in People Living with HIV in Vienna.

机构信息

Department of Social and Preventive Medicine, Centre for Public Health, Medical University of Vienna, Kinderspitalgasse 15/1, 1090, Vienna, Austria.

2nd Department of Respiratory and Critical Care, Otto Wagner Hospital, Baumgartner Höhe 1, 1140, Vienna, Austria.

出版信息

Sci Rep. 2018 May 23;8(1):8046. doi: 10.1038/s41598-018-26413-5.

DOI:10.1038/s41598-018-26413-5
PMID:29795303
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5966416/
Abstract

We aimed to determine the prevalence of drug and polydrug use in people living with HIV in Austria for the first time for which a two center cross-sectional study was performed. Participants were recruited from consecutive patients during their regularly scheduled visits. In total 438 participants were included in the analysis. For this study we used paper-pencil and online-based questionnaires. The prevalence of illicit drug use was 60.5%; with cannabis use at 31.5%, nitrates at 31.5%, sildenafil/tadalafil at 24% and cocaine at 14%, being the most used substances. Use of more than one substance (polydrug) in drug users was 69.4% or 42.0% in the total study population. Younger age, male gender, and living in an urban area were associated with drug use. Moreover, drug use during clubbing and sex, HIV therapy non-adherence and younger age were associated with polydrug use. Drug users reported condomless sex in 42.4% and performing sexual acts they would not do sober in 44.1%. Results indicate a high prevalence of illicit drug use in PLWHIV in Austria. New research focusing on illicit drug use in PLWHIV should focus on the use of substances during sex and surrounding practices.

摘要

我们旨在首次确定奥地利艾滋病毒感染者的药物和多药物使用流行率,为此进行了一项两中心横断面研究。参与者是在定期就诊期间从连续患者中招募的。共有 438 名参与者纳入分析。在这项研究中,我们使用了纸质和在线问卷。非法药物使用的流行率为 60.5%;大麻使用率为 31.5%,硝酸盐为 31.5%,西地那非/他达拉非为 24%,可卡因为 14%,是使用最多的物质。药物使用者中同时使用多种物质(多药物)的比例为 69.4%,或在总研究人群中为 42.0%。年龄较小、男性和居住在城市地区与药物使用有关。此外,在俱乐部和性行为中使用药物、HIV 治疗不依从以及年龄较小与多药物使用有关。药物使用者报告在 42.4%的性行为中没有使用安全套,在 44.1%的性行为中做了清醒时不会做的事情。结果表明,奥地利艾滋病毒感染者中非法药物使用的流行率很高。新的研究应关注艾滋病毒感染者中与性行为和相关行为有关的药物使用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3d5d/5966416/47750fa6a92a/41598_2018_26413_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3d5d/5966416/d7fdf14eb77a/41598_2018_26413_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3d5d/5966416/47750fa6a92a/41598_2018_26413_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3d5d/5966416/d7fdf14eb77a/41598_2018_26413_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3d5d/5966416/47750fa6a92a/41598_2018_26413_Fig2_HTML.jpg

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