Hammoud Mohamed A, Jin Fengyi, Lea Toby, Maher Lisa, Grierson Jeffrey, Prestage Garrett
The Kirby Institute, University of New South Wales, Kensington, NSW, Australia.
The Kirby Institute, University of New South Wales, Kensington, NSW, Australia.
J Sex Med. 2017 Jun;14(6):774-784. doi: 10.1016/j.jsxm.2017.04.670.
Gay and bisexual men (GBM) use oral erectile dysfunction medications (EDMs) often with little evidence of medical indication necessitating their use.
To investigate the prevalence, contexts, and motivations for oral EDM use and its relation to sexual risk behavior.
A total of 2,250 Australian GBM completed an online survey of licit and illicit drug use and their associated behaviors. Multivariate logistic regression analysis identified factors associated with use of EDMs in the previous 6 months and, for those who had used EDMs, factors associated with use on a weekly basis.
Any EDM use and at least weekly use in the previous 6 months.
The median age of the sample was 33.0 years (range = 16-81). Two thirds (67.7%) reported no lifetime history of EDM use. Approximately 1 in 10 participants (11.1%) had last used an EDM more than 6 months previously. In the previous 6 months, 11.5% reported using EDMs less than monthly, 5.3% reported using EDMs approximately monthly, and 4.5% reported using EDMs at least weekly. Of men who had used EDMs in the previous 6 months, common reasons cited for its use were to maintain an erection for longer (73.3%), to make it easier to "get hard" (67.3%), and difficulty in attaining or maintain an erection (53.5%). Use of EDMs in the previous 6 months was associated with illicit drug use and higher rates of sexual risk behavior. Weekly users were more likely to have severe anxiety than less frequent users.
The use of EDMs in the context of intensive sex partying, with the associated potential for increased risk of HIV transmission and illicit drug use, indicates a need to consider the use of EDMs among GBM in HIV prevention and minimizing harm.
This large-scale study of drug use among GBMs includes comprehensive detailed data on their history of use and rationales for use. Our online methodology potentially decreases social desirability bias in reporting illegal or stigmatized behaviors. This volunteer online convenience sample might not be representative of all GBMs in Australia.
GBMs who used an oral EDM in the previous 6 months often used it for recreational purposes, but many of those who used it on a weekly basis also might have used it for therapeutic reasons. GBMs often use EDMs to enhance their sexual experiences often in the context of intensive sex partying (which can include risky sexual behavior). Hammoud MA, Jin F, Lea T, et al. Off-Label Use of Phosphodiesterase Type 5 Inhibitor Erectile Dysfunction Medication to Enhance Sex Among Gay and Bisexual Men in Australia: Results From the FLUX Study. J Sex Med 2017;14:774-784.
男同性恋者和双性恋男性（GBM）常常使用口服勃起功能障碍药物（EDM），但几乎没有医学指征表明需要使用这些药物。
调查口服EDM的使用情况、背景、动机及其与性风险行为的关系。
共有2250名澳大利亚GBM完成了一项关于合法及非法药物使用及其相关行为的在线调查。多变量逻辑回归分析确定了与过去6个月内使用EDM相关的因素，对于那些使用过EDM的人，确定了与每周使用相关的因素。
过去6个月内使用过EDM和至少每周使用过EDM的情况。
样本的中位年龄为33.0岁（范围=16 - 81岁）。三分之二（67.7%）的人报告称一生中从未使用过EDM。约十分之一（11.1%）的参与者上次使用EDM是在6个月以前。在过去6个月中，11.5%的人报告使用EDM的频率低于每月一次，5.3%的人报告大约每月使用一次，4.5%的人报告至少每周使用一次。在过去6个月内使用过EDM的男性中，使用EDM的常见原因包括延长勃起时间（73.3%）、更容易“勃起”（67.3%）以及难以勃起或维持勃起（53.5%）。过去6个月内使用EDM与非法药物使用以及更高的性风险行为发生率相关。每周使用者比使用频率较低者更易出现严重焦虑。
在频繁的性派对背景下使用EDM，伴随着HIV传播风险增加和非法药物使用的可能性，这表明在预防HIV和减少危害方面需要考虑GBM中EDM的使用情况。
这项关于GBM药物使用的大规模研究包含了关于其使用历史和使用理由的全面详细数据。我们的在线研究方法可能会减少在报告非法或受污名化行为时的社会期望偏差。这个在线自愿便利样本可能不代表澳大利亚所有的GBM。
在过去6个月内使用过口服EDM的GBM通常将其用于娱乐目的，但许多每周使用的人也可能是出于治疗原因。GBM经常使用EDM来增强他们的性体验，通常是在频繁的性派对背景下（这可能包括危险性行为）。哈穆德·马、金·F、利·T等。澳大利亚男同性恋者和双性恋男性中使用5型磷酸二酯酶抑制剂勃起功能障碍药物以增强性体验的非标签使用：FLUX研究结果。《性医学杂志》2017年；14:774 - 784。
