Much Jason W, Liu Chengcheng, Piltz-Seymour Jody R
Department of Ophthalmology, University of Virginia, Charlottesville, Virginia 22908, USA.
Ophthalmology. 2008 Jul;115(7):1162-6. doi: 10.1016/j.ophtha.2007.09.004. Epub 2007 Dec 11.
To evaluate the long-term survival of visual field and visual acuity in treated glaucoma patients with end-stage glaucomatous visual field loss defined by a field constricted to a 10-degree radius or less.
Retrospective chart review.
Sixty-four patients with end-stage glaucoma.
Serial 10-2 Humphrey visual fields with size III stimulus were analyzed. The following data were recorded for each visual field: mean deviation (MD), pattern standard deviation, the largest horizontal and vertical diameters measured in degrees including only locations with thresholds of 10 decibels or more, and the number of points on the pattern deviation plot with a probability value of more than 5%.
Change in visual acuity and visual field.
Eighty-four eyes of 64 patients satisfied inclusion criteria with an average follow-up of 8.34+/-3.1 years. Seventy-eight percent of patients were black. During the study period, 14 eyes lost more than 3 lines of visual acuity. Of these 14, 8 eyes progressed to a visual acuity of 20/200 or worse. Seven eyes lost 3 decibels or more from the MD that could be reproduced over 2 visual fields.
In this predominantly black population, most treated patients with end-stage glaucoma did not demonstrate a decline in visual acuity or progressive loss of the central visual field during long-term follow-up.
评估终末期青光眼患者的视野和视力长期存活率,这些患者的青光眼性视野缺损终末期定义为视野收缩至半径10度或更小。
回顾性病历审查。
64例终末期青光眼患者。
分析采用III号刺激的系列10-2 Humphrey视野。记录每个视野的以下数据:平均偏差(MD)、模式标准差、仅包括阈值为10分贝或更高的位置所测量的最大水平和垂直直径(以度为单位),以及模式偏差图上概率值大于5%的点数。
视力和视野的变化。
64例患者的84只眼符合纳入标准,平均随访8.34±3.1年。78%的患者为黑人。在研究期间,14只眼的视力下降超过3行。在这14只眼中,8只眼的视力进展至20/200或更差。7只眼的MD值在两个视野中可重复下降3分贝或更多。
在这个以黑人为主的人群中,大多数接受治疗的终末期青光眼患者在长期随访期间未出现视力下降或中央视野逐渐丧失。