Hermann Bruce P, Jones Jana, Sheth Raj, Seidenberg Michael
Department of Neurology, University of Wisconsin School of Medicine and Public Health, Madison 53792, USA.
Semin Pediatr Neurol. 2007 Dec;14(4):173-80. doi: 10.1016/j.spen.2007.08.003.
This paper addresses the issue of cognitive morbidity and abnormalities in quantitative MR volumetric in children with new and recent onset idiopathic epilepsy. The available literature suggests that mild diffuse cognitive problems are evident in children with new onset epilepsy in the context of intact whole brain and lobar volumetrics. Subsets of children can be identified with salient academic and volumetric abnormalities. These findings represent the baseline upon which any subsequent effects of chronic epilepsy may accrue.
本文探讨了新发和近期发作的特发性癫痫患儿的认知发病率问题以及定量磁共振体积测量中的异常情况。现有文献表明,在全脑和脑叶体积测量正常的情况下,新发癫痫患儿存在明显的轻度弥漫性认知问题。可以识别出一部分在学业和体积测量方面有显著异常的儿童。这些发现代表了慢性癫痫后续可能产生任何影响的基线。