蛋白质结构预测结果的评估。
The evaluation of protein structure prediction results.
作者信息
Cozzetto Domenico, Giorgetti Alejandro, Raimondo Domenico, Tramontano Anna
机构信息
Department of Biochemical Sciences Rossi Fanelli, University of Rome La Sapienza, P. le A. Moro, 5, 00185, Rome, Italy.
出版信息
Mol Biotechnol. 2008 May;39(1):1-8. doi: 10.1007/s12033-007-9023-6. Epub 2007 Dec 11.
Methods for protein structure prediction are flourishing and becoming widely available to both experimentalists and computational biologists. However, how good are they? What is their range of applicability and how can we know which method is better suited for the task at hand? These are the questions that this review tries to address, by describing the worldwide Critical Assessment of techniques for protein Structure Prediction (CASP) initiative and focusing on the specific problems of assessing the quality of a protein 3D model.
蛋白质结构预测方法正在蓬勃发展，并且实验人员和计算生物学家都能广泛使用。然而，这些方法的效果如何？它们的适用范围是什么，我们又如何知道哪种方法更适合手头的任务？本综述试图通过描述全球蛋白质结构预测技术关键评估（CASP）计划，并聚焦于评估蛋白质三维模型质量的具体问题来回答这些问题。
Zotero 插件