Orom Heather, Coté Michele L, González Hector M, Underwood Willie, Schwartz Ann G
Karmanos Cancer Institute, Wayne State University, Detroit, Michigan 48201, USA.
Cancer. 2008 Jan 15;112(2):399-406. doi: 10.1002/cncr.23173.
Patients' self-reports of family history of cancer influence physician cancer screening recommendations. Little is known about rates of reporting a family history of cancer in the immigrant population.
The study used a nationally representative probability sample of adults, 18 years of age and older, living in the United States (N=5010) who had responded to the 2005 Health Information Trends Survey (HINTS). Likelihood of reporting a family history of cancer was examined as a function of nativity status (foreign-born vs US-born) and control variables.
Immigrants were approximately one-third as likely as nonimmigrants to report a family history of cancer (odds ratio [OR], 0.35; 95% confidence index [95% CI], 0.25-0.48) after controlling for sociodemographic and cancer knowledge variables.
When healthcare providers are assessing cancer risk and making screening recommendations, they should take into account that among foreign-born patients, and especially nonwhite foreign-born patients, self-reported family history of cancer (FHC) may misrepresent their cancer risk. Failure to account for low rates of reporting FHC among immigrants could inadvertently contribute to existing disparities in cancer screening and use of genetic testing by immigrants and ethnic minorities.
患者对癌症家族史的自我报告影响医生的癌症筛查建议。对于移民人群中癌症家族史的报告率知之甚少。
该研究使用了一个具有全国代表性的概率样本，样本为居住在美国的18岁及以上成年人（N = 5010），他们对2005年健康信息趋势调查（HINTS）做出了回应。将报告癌症家族史的可能性作为出生状态（外国出生与美国出生）和控制变量的函数进行研究。
在控制了社会人口统计学和癌症知识变量后，移民报告癌症家族史的可能性约为非移民的三分之一（优势比[OR]，0.35；95%置信区间[95%CI]，0.25 - 0.48）。
当医疗保健提供者评估癌症风险并提出筛查建议时，他们应考虑到在外国出生的患者中，尤其是非白人外国出生的患者，自我报告的癌症家族史（FHC）可能无法准确反映他们的癌症风险。未能考虑移民中FHC报告率低的情况可能会无意中加剧移民和少数族裔在癌症筛查和基因检测使用方面现有的差异。
