Göbel Werner, Helmchen Fritjof
Department of Neurophysiology, Brain Research Institute, University of Zurich, Zurich, Switzerland.
Physiology (Bethesda). 2007 Dec;22:358-65. doi: 10.1152/physiol.00032.2007.
Spatiotemporal activity patterns in local neural networks are fundamental to brain function. Network activity can now be measured in vivo using two-photon imaging of cell populations that are labeled with fluorescent calcium indicators. In this review, we discuss basic aspects of in vivo calcium imaging and highlight recent developments that will help to uncover operating principles of neural circuits.
局部神经网络中的时空活动模式是脑功能的基础。现在可以使用对用荧光钙指示剂标记的细胞群体进行双光子成像的方法在体内测量网络活动。在这篇综述中，我们讨论了体内钙成像的基本方面，并重点介绍了有助于揭示神经回路工作原理的最新进展。
