Johansson C B, Albrektsson T
Biomaterials Group, Department of Handicap Research, University of Göteborg, Sweden.
Clin Oral Implants Res. 1991 Jan-Mar;2(1):24-9. doi: 10.1034/j.1600-0501.1991.020103.x.
Screw-shaped commercially pure (c.p.) niobium and c.p. titanium implants were inserted in rabbit bone. After a healing period of 3 months, a significantly higher removal torque was demonstrated to unscrew the niobium implants (average 32.9 Ncm) compared to the c.p. titanium implants (average 25.3 Ncm). In the histomorphometric part of the study, there were no significant differences in bone-to-metal contact between the 2 implant materials. An average of 41.1% bony contact was demonstrated for the niobium screws compared to an average of 37.2% for the c.p. titanium ones. Our removal torque findings could be related to the differences that we observed between the 2 implant surfaces as indicated by SEM. Since niobium implants showed a more irregular surface topography and niobium is a softer metal than c.p. titanium, this seems the most probable reason for the differences observed in removal torque between the 2 metals. Hypothetically, a more "positive biocompatibility" of the c.p. niobium in comparison to the c.p. titanium remains as another possible reason for the observed differences. However, against such a difference in biocompatibility between c.p. niobium and c.p. titanium, there is the very similar amount of bony contact registered in the histomorphometric analysis.
将螺旋形商业纯铌和商业纯钛植入物植入兔骨中。经过3个月的愈合期后，结果显示，拧下铌植入物所需的去除扭矩（平均32.9牛厘米）显著高于商业纯钛植入物（平均25.3牛厘米）。在该研究的组织形态计量学部分，两种植入材料的骨与金属接触无显著差异。铌螺钉的骨接触平均为41.1%，而商业纯钛螺钉的平均骨接触为37.2%。我们的去除扭矩研究结果可能与扫描电子显微镜（SEM）显示的两种植入物表面差异有关。由于铌植入物表面形貌更不规则，且铌是比商业纯钛更软的金属，这似乎是两种金属去除扭矩差异的最可能原因。假设，商业纯铌与商业纯钛相比具有更“积极的生物相容性”，这仍然是观察到的差异的另一个可能原因。然而，与商业纯铌和商业纯钛之间这种生物相容性差异相悖的是，组织形态计量分析中记录的骨接触量非常相似。
