Lunde Ottar, Tanbo Tom
Department of Gynecology and Obstetrics, National Resource Centre for Women's Health, Rikshospitalet Medical Centre, Oslo, Norway.
Gynecol Endocrinol. 2007 Dec;23(12):704-9. doi: 10.1080/09513590701705189.
The aim of the present study was to examine the occurrence of possibly associated diseases in 149 women with polycystic ovary syndrome (PCOS) 15-25 years after ovarian wedge resection. Diabetes mellitus was the only associated disease which showed a significantly increased occurrence. No significant change in cancers specific for the female gender was seen. Likewise, the relative risk of cardiovascular disease was not affected. However, the power of the statistical test was low. This long-term study indicates increased risk of diabetes mellitus in PCOS patients. The study group is too small to give any conclusions about other possibly associated diseases. Family histories, however, revealed that associated diseases are related to genetic disposition rather than to PCOS per se.
本研究的目的是调查149例多囊卵巢综合征（PCOS）患者在卵巢楔形切除术后15 - 25年可能伴发疾病的发生情况。糖尿病是唯一一种发生率显著增加的伴发疾病。未发现女性特有的癌症有显著变化。同样，心血管疾病的相对风险也未受影响。然而，统计检验的效能较低。这项长期研究表明PCOS患者患糖尿病的风险增加。研究组规模太小，无法就其他可能的伴发疾病得出任何结论。不过，家族病史显示，伴发疾病与遗传易感性有关，而非与PCOS本身有关。
