Rizzo Manfredi, Berneis Kaspar, Spinas Giatgen, Rini Giovam Battista, Carmina Enrico
Department of Internal Medicine and Emerging Diseases, University of Palermo, Palermo, Italy.
Fertil Steril. 2009 Apr;91(4 Suppl):1563-7. doi: 10.1016/j.fertnstert.2008.09.070. Epub 2008 Oct 30.
Most available data suggest that the prevalence of cardiovascular diseases in women with polycystic ovary syndrome (PCOS) is smaller than expected based on risk calculations during fertile years; therefore, more studies are needed on long-term cardiovascular consequences. Evidence is accumulating that postmenopausal women with PCOS have an increased risk of cerebrovascular events and cardiovascular morbidity. These events are partially related to persisting hyperandrogenism but are mostly correlated with excessive body weight (mainly visceral obesity); this suggests that our best long-term strategy is to ensure that women with PCOS are informed about their high risk for metabolic and cardiovascular diseases.
大多数现有数据表明，多囊卵巢综合征（PCOS）女性心血管疾病的患病率低于根据生育期风险计算预期的水平；因此，需要更多关于长期心血管后果的研究。越来越多的证据表明，绝经后PCOS女性发生脑血管事件和心血管疾病的风险增加。这些事件部分与持续的高雄激素血症有关，但大多与体重超标（主要是内脏肥胖）相关；这表明我们最佳的长期策略是确保让PCOS女性了解她们患代谢和心血管疾病的高风险。
