Warburton Darren E R, Nicol Crystal Whitney, Gatto Stephanie N, Bredin Shannon S D
Cardiovascular Physiology and Rehabilitation Laboratory, Faculty of Medicine, University of British Columbia,Vancouver, BC, Canada.
Vasc Health Risk Manag. 2007;3(5):673-89.
In this narrative review of the current literature, we examine the traditional risk factors and patient profiles leading to cardiovascular disease and osteoporosis. We discuss the interrelationships between risk factors and common pathophysiological mechanisms for cardiovascular disease and osteoporosis. We evaluate the increasing evidence that supports an association between these disabling conditions. We reveal that vascular health appears to have a strong effect on skeletal health, and vice versa. We highlight the importance of addressing the risk benefit of preventative interventions in both conditions. We discuss how both sexes are affected by these chronic conditions and the importance of considering the unique risk of the individual. We show that habitual physical activity is an effective primary and secondary preventative strategy for both cardiovascular disease and osteoporosis. We highlight how a holistic approach to the prevention and treatment of these chronic conditions is likely warranted.
在这篇对当前文献的叙述性综述中，我们研究了导致心血管疾病和骨质疏松症的传统风险因素及患者特征。我们讨论了心血管疾病和骨质疏松症风险因素之间的相互关系以及常见的病理生理机制。我们评估了越来越多支持这两种致残性疾病之间存在关联的证据。我们发现血管健康似乎对骨骼健康有很强的影响，反之亦然。我们强调了在这两种情况下考虑预防性干预的风险效益的重要性。我们讨论了这两种慢性病如何影响两性以及考虑个体独特风险的重要性。我们表明，习惯性体育活动是预防心血管疾病和骨质疏松症的有效一级和二级预防策略。我们强调，对这些慢性病的预防和治疗采用整体方法可能是必要的。
