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萘暴露的现有数据:优势与局限

Available data on naphthalene exposures: strengths and limitations.

作者信息

Price Paul S, Jayjock Michael A

机构信息

The LifeLine Group, Inc., USA.

出版信息

Regul Toxicol Pharmacol. 2008 Jul;51(2 Suppl):S15-21. doi: 10.1016/j.yrtph.2007.10.010. Epub 2007 Dec 19.

Abstract

Exposures to naphthalene occur from a number of sources. Data on these exposures have been reported by a number of researchers; however, these data have not been organized into a consistent framework. In addition, while naphthalene has been identified as an animal inhalation carcinogen there has been no attempt to define the ranges of long-term average inhalation exposures for the general population or sub populations that are relevant to the assessment of the risk of the occurrence of chronic effects. This paper attempts to organize the available data on naphthalene levels in air and provide ranges for the long-term average concentrations experienced by different populations. The paper also discusses the limitations of available data and identifies areas for future research.

摘要

萘的接触源多种多样。许多研究人员已报告了这些接触的数据;然而,这些数据尚未被整理成一个统一的框架。此外,虽然萘已被确定为一种动物吸入性致癌物,但尚未有人尝试界定与评估慢性影响发生风险相关的一般人群或亚人群的长期平均吸入接触范围。本文试图整理关于空气中萘含量的现有数据,并提供不同人群所经历的长期平均浓度范围。本文还讨论了现有数据的局限性,并确定了未来研究的领域。

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