Orhue Augustine, Aziken Michael
Human Reproduction Research Program Unit, Department of Obstetrics and Gynecology, University of Benin Teaching Hospital, Benin City, Edo State, Nigeria.
Int J Gynaecol Obstet. 2008 Apr;101(1):11-5. doi: 10.1016/j.ijgo.2007.09.034. Epub 2008 Feb 20.
To assess outcome at an infertility management center in Nigeria.
Diagnoses were made for 1948 consecutive couples following the World Health Organization guideline on the investigation of infertile couples, treatment was provided, and the couples were followed up over a 10-year period.
The infertility was primary in 14.3% and secondary in 85.7% of cases. Treatment failed in 59.9% and succeeded in 40.1% of cases, resulting in pregnancy for 13.5% of the couples with female infertility factors alone, 6.5% of the couples with male infertility factors alone, and 3.6% of those with both male and female factors. The pregnancy rate was 16.6% for couples with idiopathic infertility.
Pregnancy outcome was relatively poor because conventional treatments did not cure the most prevalent causes of infertility, and assisted reproductive technology is therefore advocated.
评估尼日利亚一家不孕不育管理中心的治疗结果。
按照世界卫生组织关于不孕夫妇调查的指南，对1948对连续就诊的夫妇进行诊断，给予治疗，并对这些夫妇进行了为期10年的随访。
14.3%的病例为原发性不孕，85.7%为继发性不孕。59.9%的病例治疗失败，40.1%成功，仅女方有不孕因素的夫妇中13.5%怀孕，仅男方有不孕因素的夫妇中6.5%怀孕，男女双方均有因素的夫妇中3.6%怀孕。特发性不孕夫妇的妊娠率为16.6%。
妊娠结局相对较差，因为传统治疗方法无法治愈最常见的不孕原因，因此提倡辅助生殖技术。
