Suppr超能文献

摩洛哥人群中的不孕症:拉巴特生殖健康中心的一项病因学研究。

Infertility in the Moroccan population: an etiological study in the reproductive health centre in Rabat.

作者信息

Benbella Amal, Aboulmakarim Siham, Hardizi Houyam, Zaidouni Asmaa, Bezad Rachid

机构信息

Assisted Reproductive Technology Unit of the Reproductive Health Centre, University Hospital Ibn Sina, Rabat, Morocco.

Laboratory of Medical Biotechnology (Med Biotech), Faculty of Medicine and Pharmacy, University Mohamed V, Rabat, Morocco.

出版信息

Pan Afr Med J. 2018 Jul 10;30:204. doi: 10.11604/pamj.2018.30.204.13498. eCollection 2018.

Abstract

The causes of infertility vary widely and differ between regions and within countries. There is no report on this subject in Morocco. Therefore, the aim of this study was to determine the causes of infertility in Moroccan infertile couples and to compare the findings with data from the various published studies. This retrospective study included 1265 infertile couples who attended the Assisted Reproductive Technology Unit of the Reproductive Health Centre of the University Hospital Ibn Sina in Rabat. All couples had been infertile for at least 1 year and both partners were fully investigated. The median duration of infertility was 5 ± 4 years. Couples had primary and secondary infertility in 77.2% and 22.8% of cases, respectively. Among the 1265 couples, 39.6% had a female factor, 28.2% had a male factor, 17% had both male and female factors and in 15.2% of couples, the cause of infertility was undetermined. The most common causes of male infertility were varicocele (14.3%), obstructive azoospermia (7%), Congenital anomalies (5.5%) and male accessory gland infection (4%). Results showed that 54.8% of men had a normal semen analysis. Among women, infertility factors were ovulatory disorders (27.5%), tubal factor (26.6%), uterine factor (12.6%), endometriosis (4.1%), and 43.4% of women were normal. The causes of infertility in this study are comparable with those reported by the World Health Organization and other studies. However, the substantial delay before attending an infertility clinic highlighted by the study needs additional consideration.

摘要

不孕不育的原因多种多样,因地区和国家内部而异。摩洛哥尚无关于该主题的报告。因此,本研究的目的是确定摩洛哥不孕不育夫妇的不孕原因,并将研究结果与各项已发表研究的数据进行比较。这项回顾性研究纳入了1265对不孕不育夫妇,他们前往拉巴特伊本·西那大学医院生殖健康中心的辅助生殖技术科就诊。所有夫妇均不孕至少1年,且双方均接受了全面检查。不孕的中位持续时间为5±4年。夫妇中,原发性不孕和继发性不孕分别占77.2%和22.8%。在这1265对夫妇中,39.6%存在女性因素,28.2%存在男性因素,17%男女双方均有因素,15.2%的夫妇不孕原因不明。男性不育最常见的原因是精索静脉曲张(14.3%)、梗阻性无精子症(7%)、先天性异常(5.5%)和男性附属腺感染(4%)。结果显示,54.8%的男性精液分析正常。在女性中,不孕因素包括排卵障碍(27.5%)、输卵管因素(26.6%)、子宫因素(12.6%)、子宫内膜异位症(4.1%),43.4%的女性正常。本研究中不孕不育的原因与世界卫生组织及其他研究报告的原因相当。然而,该研究强调的就诊不孕不育诊所前的显著延迟需要进一步考虑。

相似文献

1
Infertility in the Moroccan population: an etiological study in the reproductive health centre in Rabat.
Pan Afr Med J. 2018 Jul 10;30:204. doi: 10.11604/pamj.2018.30.204.13498. eCollection 2018.
2
Infertility in the Moroccan population: major risk factors encountered in the reproductive health centre in Rabat.
Pan Afr Med J. 2018 Jul 5;30:195. doi: 10.11604/pamj.2018.30.195.13849. eCollection 2018.
5
Clinical patterns and major causes of infertility in Mongolia.
J Obstet Gynaecol Res. 2004 Oct;30(5):386-93. doi: 10.1111/j.1447-0756.2004.00217.x.
6
Resolution of infertility and number of children: 1386 couples followed for a median of 13 years.
Hum Reprod. 2017 Oct 1;32(10):2042-2048. doi: 10.1093/humrep/dex271.
7
Worldwide patterns of infertility: is Africa different?
Lancet. 1985 Sep 14;2(8455):596-8. doi: 10.1016/s0140-6736(85)90594-x.
9
[Prevalence of male infertility in a university hospital in Morocco].
Pan Afr Med J. 2021 Jan 15;38:46. doi: 10.11604/pamj.2021.38.46.19633. eCollection 2021.
10
Screening for infertility in Indonesia. Results of examination of 863 infertile couples.
Andrologia. 1978 Sep-Oct;10(5):405-12. doi: 10.1111/j.1439-0272.1978.tb03059.x.

引用本文的文献

1
Journey of infertile couples: scoping the barriers for infertility care among infertile women in Morocco.
Obstet Gynecol Sci. 2025 May;68(3):186-197. doi: 10.5468/ogs.24259. Epub 2025 Mar 25.
2
Experiences of infertility among couples in Morocco.
Front Reprod Health. 2025 Jan 7;6:1513243. doi: 10.3389/frph.2024.1513243. eCollection 2024.
3
Embracing the mental health challenges of uterus transplant candidates.
Acta Obstet Gynecol Scand. 2025 Mar;104(3):540-547. doi: 10.1111/aogs.15038. Epub 2025 Jan 16.
5
Uterine Factor Infertility, a Systematic Review.
J Clin Med. 2022 Aug 21;11(16):4907. doi: 10.3390/jcm11164907.
6
Access to infertility care services towards Universal Health Coverage is a right and not an option.
BMC Health Serv Res. 2022 Aug 25;22(1):1089. doi: 10.1186/s12913-022-08456-7.
8
Effect of Filgrastim on adult male rats' fertility and reproductive performance.
Saudi J Biol Sci. 2021 Apr;28(4):2558-2565. doi: 10.1016/j.sjbs.2021.01.060. Epub 2021 Feb 11.

本文引用的文献

1
Is the oocyte quality affected by endometriosis? A review of the literature.
J Ovarian Res. 2017 Jul 12;10(1):43. doi: 10.1186/s13048-017-0341-4.
2
Causes of male infertility: a 9-year prospective monocentre study on 1737 patients with reduced total sperm counts.
Hum Reprod. 2017 Jan;32(1):18-31. doi: 10.1093/humrep/dew284. Epub 2016 Nov 17.
3
Impact of female age and nulligravidity on fecundity in an older reproductive age cohort.
Fertil Steril. 2016 Jun;105(6):1584-1588.e1. doi: 10.1016/j.fertnstert.2016.02.028. Epub 2016 Mar 5.
5
Incidence of infertility and risk factors of impaired fecundity among newly married couples in a Chinese population.
Reprod Biomed Online. 2015 Jan;30(1):92-100. doi: 10.1016/j.rbmo.2014.10.002. Epub 2014 Oct 13.
7
Anti-Müllerian hormone (AMH) is a strong predictor of live birth in women undergoing assisted reproductive technology.
Reprod Biol. 2014 Sep;14(3):176-81. doi: 10.1016/j.repbio.2014.03.004. Epub 2014 Apr 19.
9
Experience with a comprehensive university hospital-based infertility program in Nigeria.
Int J Gynaecol Obstet. 2008 Apr;101(1):11-5. doi: 10.1016/j.ijgo.2007.09.034. Epub 2008 Feb 20.
10
Infertility among couples in a population-based study in Iran: prevalence and associated risk factors.
Int J Androl. 2008 Jun;31(3):303-14. doi: 10.1111/j.1365-2605.2007.00764.x. Epub 2007 May 7.

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验