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Pol II degradation activates cell death independently from the loss of transcription.
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Herpes simplex virus 1 inhibits phosphorylation of RNA polymerase II CTD serine-7.
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RNA Pol II Assembly Affects ncRNA Expression.
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IntS6 and the Integrator phosphatase module tune the efficiency of select premature transcription termination events.
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Phosphorylation and functions of the RNA polymerase II CTD.
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P-TEFb is not an essential elongation factor for the intronless human U2 snRNA and histone H2b genes.
EMBO J. 2005 Dec 7;24(23):4154-65. doi: 10.1038/sj.emboj.7600876. Epub 2005 Nov 24.
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Integrator, a multiprotein mediator of small nuclear RNA processing, associates with the C-terminal repeat of RNA polymerase II.
Cell. 2005 Oct 21;123(2):265-76. doi: 10.1016/j.cell.2005.08.019.
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Role of the mammalian RNA polymerase II C-terminal domain (CTD) nonconsensus repeats in CTD stability and cell proliferation.
Mol Cell Biol. 2005 Sep;25(17):7665-74. doi: 10.1128/MCB.25.17.7665-7674.2005.
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A CPSF-73 homologue is required for cell cycle progression but not cell growth and interacts with a protein having features of CPSF-100.
Mol Cell Biol. 2005 Feb;25(4):1489-500. doi: 10.1128/MCB.25.4.1489-1500.2005.
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3'-box-dependent processing of human pre-U1 snRNA requires a combination of RNA and protein co-factors.
Nucleic Acids Res. 2004 Jun 1;32(10):2987-94. doi: 10.1093/nar/gkh619. Print 2004.
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Role of the C-terminal domain of RNA polymerase II in U2 snRNA transcription and 3' processing.
Mol Cell Biol. 2004 Jan;24(2):846-55. doi: 10.1128/MCB.24.2.846-855.2004.
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The CTD code.
Nat Struct Biol. 2003 Sep;10(9):679-80. doi: 10.1038/nsb0903-679.
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A 10 residue motif at the C-terminus of the RNA pol II CTD is required for transcription, splicing and 3' end processing.
EMBO J. 2003 Aug 15;22(16):4274-82. doi: 10.1093/emboj/cdg396.
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Analysis of the stimulatory effect of splicing on mRNA production and utilization in mammalian cells.
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